Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 14 September 1984:
Vol. 225. no. 4667, pp. 1166 - 1168
DOI: 10.1126/science.6433482
Prev | Table of Contents | Next

Articles

Science, Vol 225, Issue 4667, 1166-1168
Copyright © 1984 by American Association for the Advancement of Science

articles

Cell surface changes associated with cellular immune reactions in Drosophila

AJ Nappi and M Silvers

In Drosophila melanogaster a temperature-induced change in immune competence accompanies cell surface alterations that cause its blood cells to adhere and to encapsulate a parasite. At 29 degrees C the blood cells of the tumorous-lethal (Tuml) mutant show a high degree of immune competence and encapsulate the eggs of the parasitic wasp Leptopilina heterotoma. At 21 degrees C the blood cells are essentially immune incompetent. High percentages of lectin binding cells were found under conditions which potentiated cellular encapsulation responses. Some immune reactive blood cells did not bind lectin. The low percentages of lectin binding cells in susceptible hosts suggest that developing parasites alter the cell surface of the blood cells of immune reactive hosts.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Functional Evolution of the Vertebrate Myb Gene Family: B-Myb, but Neither A-Myb nor c-Myb, Complements Drosophila Myb in Hemocytes.
C. J. Davidson, R. Tirouvanziam, L. A. Herzenberg, and J. S. Lipsick (2005)
Genetics 169, 215-229
   Abstract »    Full Text »    PDF »
Helix pomatia Lectin, an Inducer of Drosophila Immune Response, Binds to Hemomucin, a Novel Surface Mucin.
U. Theopold, C. Samakovlis, H. Erdjument-Bromage, N. Dillon, B. Axelsson, O. Schmidt, P. Tempst, and D. Hultmark (1996)
J. Biol. Chem. 271, 12708-12715
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)