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Science 7 September 1984:
Vol. 225. no. 4666, pp. 1050 - 1052
DOI: 10.1126/science.6591429
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Articles

Science, Vol 225, Issue 4666, 1050-1052
Copyright © 1984 by American Association for the Advancement of Science

articles

Prostaglandin E2: a neuromodulator in the central control of gastrointestinal motility and feeding behavior by calcitonin

MJ Fargeas, J Fioramonti, and L Bueno

Two micrograms of prostaglandin E2 injected into the lateral ventricle of the brain in rats had the same anorectic and gastrointestinal motor effect as central administration of 0.02 unit of calcitonin. The effects of calcitonin were blocked by a previous intracerebroventricular administration of 0.25 milligram of indomethacin. These results suggest that both anorectic and gastrointestinal motor effects of calcitonin are centrally mediated by the release of prostaglandins.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Cytokines and the Anorexia of Infection: Potential Mechanisms and Treatments.
D. O. McCarthy (2000)
Biol Res Nurs 1, 287-298
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)