Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 17 August 1984:
Vol. 225. no. 4663, pp. 721 - 723
DOI: 10.1126/science.6087454
Prev | Table of Contents | Next

Articles

Science, Vol 225, Issue 4663, 721-723
Copyright © 1984 by American Association for the Advancement of Science

articles

A cell line expressing vesicular stomatitis virus glycoprotein fuses at low pH

RZ Florkiewicz and JK Rose

A stable cell line expressing a complementary DNA clone encoding the vesicular stomatitis virus glycoprotein fused and formed polykaryons at pH 5.5. The formation of polykaryons was dependent on the presence of glycoprotein anchored at the cell surface and could be prevented by incubation of cells with a monoclonal antibody to the glycoprotein. Fusion occurred at a pH 0.5 unit lower than that observed for cells infected with vesicular stomatitis virus.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Hybrid alphavirus-rhabdovirus propagating replicon particles are versatile and potent vaccine vectors.
N. F. Rose, J. Publicover, A. Chattopadhyay, and J. K. Rose (2008)
PNAS 105, 5839-5843
   Abstract »    Full Text »    PDF »
Fusogenicity of Jaagsiekte Sheep Retrovirus Envelope Protein Is Dependent on Low pH and Is Enhanced by Cytoplasmic Tail Truncations.
M. Cote, Y.-M. Zheng, L. M. Albritton, and S.-L. Liu (2008)
J. Virol. 82, 2543-2554
   Abstract »    Full Text »    PDF »
Fusion of microglia with pyramidal neurons after retroviral infection..
J. B. Ackman, F. Siddiqi, R. S. Walikonis, and J. J. LoTurco (2006)
J. Neurosci. 26, 11413-11422
   Abstract »    Full Text »    PDF »
A Single-Cycle Vaccine Vector Based on Vesicular Stomatitis Virus Can Induce Immune Responses Comparable to Those Generated by a Replication-Competent Vector.
J. Publicover, E. Ramsburg, and J. K. Rose (2005)
J. Virol. 79, 13231-13238
   Abstract »    Full Text »    PDF »
Prediction and Identification of a Permissive Epitope Insertion Site in the Vesicular Stomatitis Virus Glycoprotein.
L. D. Schlehuber and J. K. Rose (2004)
J. Virol. 78, 5079-5087
   Abstract »    Full Text »    PDF »
Generation of Transduction-Competent Retroviral Vectors by Infection with a Single Hybrid Vaccinia Virus.
C. Konetschny, G. W. Holzer, C. Urban, T. Hammerle, J. Mayrhofer, and F. G. Falkner (2003)
J. Virol. 77, 7017-7025
   Abstract »    Full Text »    PDF »
Roles for Endocytosis and Low pH in Herpes Simplex Virus Entry into HeLa and Chinese Hamster Ovary Cells.
A. V. Nicola, A. M. McEvoy, and S. E. Straus (2003)
J. Virol. 77, 5324-5332
   Abstract »    Full Text »    PDF »
Membrane Fusion Induced by Vesicular Stomatitis Virus Depends on Histidine Protonation.
F. A. Carneiro, F. Stauffer, C. S. Lima, M. A. Juliano, L. Juliano, and A. T. Da Poian (2003)
J. Biol. Chem. 278, 13789-13794
   Abstract »    Full Text »    PDF »
Infectivity of a Human Respiratory Syncytial Virus Lacking the SH, G, and F Proteins Is Efficiently Mediated by the Vesicular Stomatitis Virus G Protein.
A. G. P. Oomens, A. G. Megaw, and G. W. Wertz (2003)
J. Virol. 77, 3785-3798
   Abstract »    Full Text »    PDF »
The Membrane-Proximal Domain of Vesicular Stomatitis Virus G Protein Functions as a Membrane Fusion Potentiator and Can Induce Hemifusion.
E. Jeetendra, C. S. Robison, L. M. Albritton, and M. A. Whitt (2002)
J. Virol. 76, 12300-12311
   Abstract »    Full Text »    PDF »
Measurement of membrane fusion activity from viral membrane fusion proteins based on a fusion-dependent promoter induction system in insect cells.
J. M. Slack and G. W. Blissard (2001)
J. Gen. Virol. 82, 2519-2529
   Abstract »    Full Text »    PDF »
Pseudotyping of Glycoprotein D-Deficient Herpes Simplex Virus Type 1 with Vesicular Stomatitis Virus Glycoprotein G Enables Mutant Virus Attachment and Entry.
D. B. Anderson, S. Laquerre, W. F. Goins, J. B. Cohen, and J. C. Glorioso (2000)
J. Virol. 74, 2481-2487
   Abstract »    Full Text »
Vesicular Stomatitis Virus G Protein Acquires pH-Independent Fusion Activity during Transport in a Polarized Endometrial Cell Line.
P. C. Roberts, T. Kipperman, and R. W. Compans (1999)
J. Virol. 73, 10447-10457
   Abstract »    Full Text »
Replication-Competent Rhabdoviruses with Human Immunodeficiency Virus Type 1 Coats and Green Fluorescent Protein: Entry by a pH-Independent Pathway.
E. Boritz, J. Gerlach, J. E. Johnson, and J. K. Rose (1999)
J. Virol. 73, 6937-6945
   Abstract »    Full Text »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)