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Science 17 August 1984:
Vol. 225. no. 4663, pp. 718 - 721
DOI: 10.1126/science.6463648
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Articles
Science, Vol 225, Issue 4663, 718-721
Copyright © 1984 by American Association for the Advancement of Science
Nuclear localization and DNA binding properties of a protein expressed by human c-myc oncogene
H Persson
and
P Leder
Antisera to the human cellular myc oncogene product were used to identify a human c-myc specific protein with a molecular weight of 65,000. Subcellular fractionation showed that the human c-myc protein is predominantly found in the cell nucleus. The p65Kc-myc protein binds to double- and single-stranded DNA as measured by a DNA affinity chromatography assay.
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