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Science 29 June 1984:
Vol. 224. no. 4656, pp. 1433 - 1436
DOI: 10.1126/science.6374897
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Articles

Science, Vol 224, Issue 4656, 1433-1436
Copyright © 1984 by American Association for the Advancement of Science

articles

Identification and location of brain protein 4.1

Goodman SR, LA Casoria, DB Coleman, and IS Zagon

Protein 4.1 is a membrane skeletal protein that converts the low-affinity interaction between spectrin and actin into a high-affinity ternary complex of spectrin, protein 4.1, and actin that is essential to the structural stability of the erythrocyte. Pig brain was shown to contain an 87-kilodalton immunoreactive analog of protein 4.1 that has partial sequence homology with pig erythrocyte protein 4.1 and the same location as spectrin in the cortical cytoplasm of neuronal and glial cell types of the cerebellum.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
A Novel Neuron-Enriched Homolog of the Erythrocyte Membrane Cytoskeletal Protein 4.1.
L. D. Walensky, S. Blackshaw, D. Liao, C. C. Watkins, H.-U. G. Weier, M. Parra, R. L. Huganir, J. G. Conboy, N. Mohandas, and S. H. Snyder (1999)
J. Neurosci. 19, 6457-6467
   Abstract »    Full Text »    PDF »
The 13-kD FK506 Binding Protein, FKBP13, Interacts with a Novel Homologue of the Erythrocyte Membrane Cytoskeletal Protein 4.1.
L. D. Walensky, P. Gascard, M. E. Field, S. Blackshaw, J. G. Conboy, N. Mohandas, and S. H. Snyder (1998)
J. Cell Biol. 141, 143-153
   Abstract »    Full Text »    PDF »


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