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Science 27 April 1984:
Vol. 224. no. 4647, pp. 390 - 392
DOI: 10.1126/science.6608789
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Articles

Science, Vol 224, Issue 4647, 390-392
Copyright © 1984 by American Association for the Advancement of Science

articles

Rectal insemination modifies immune responses in rabbits

JM Richards, JM Bedford, and SS Witkin

Weekly deposition of pooled rabbit semen into the rectum in healthy male rabbits resulted in the appearance of immune complexes and antibodies to sperm and to peripheral blood lymphocyte antigens. It also led to a decreased ability to mount a humoral immune response to T lymphocyte-dependent antigens, keyhole limpet hemocyanin, and sheep red blood cells. These findings suggest that repeated rectal deposition of semen may compromise some aspects of the immune system.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)