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Science 9 March 1984:
Vol. 223. no. 4640, pp. 1077 - 1079
DOI: 10.1126/science.6695194
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Articles

Science, Vol 223, Issue 4640, 1077-1079
Copyright © 1984 by American Association for the Advancement of Science

articles

Dioxin in soil: bioavailability after ingestion by rats and guinea pigs

EE McConnell, GW Lucier, RC Rumbaugh, PW Albro, DJ Harvan, Hass JR, and MW Harris

Soil environmentally contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was given by gavage to guinea pigs and rats. The development of a characteristic clinicopathologic syndrome in guinea pigs, the induction of aryl hydrocarbon hydroxylase in rats, and the presence of TCDD in the livers of both species show that TCDD in soil exhibits high biological availability after ingestion.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Bioavailability of the Genotoxic Components in Coal Tar Contaminated Soils in Fischer 344 Rats.
N. R. Bordelon, K. C. Donnelly, L. C. King, D. C. Wolf, W. R. Reeves, and S. E. George (2000)
Toxicol. Sci. 56, 37-48
   Abstract »    Full Text »    PDF »
Regulations and Advisories.
(2000)
Toxicology and Industrial Health 16, 173-201
   PDF »
Bioavailability of dioxin in soil from a 2,4,5-T manufacturing site.
T. Umbreit, E. Hesse, and M. Gallo (1986)
Science 232, 497-499
   Abstract »    PDF »


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