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Science 2 March 1984:
Vol. 223. no. 4639, pp. 938 - 940
DOI: 10.1126/science.6141639
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Articles

Science, Vol 223, Issue 4639, 938-940
Copyright © 1984 by American Association for the Advancement of Science

articles

Estradiol is concentrated in tyrosine hydroxylase-containing neurons of the hypothalamus

M Sar

Localization of [3H]estradiol in tyrosine hydroxylase-containing neurons of rat brain was shown by a combined technique of autoradiography and immunohistochemistry. [3H]Estradiol was concentrated in the nuclei of tyrosine hydroxylase-containing neurons in the nucleus arcuatus, nucleus periventricularis hypothalami, and the zona incerta. These results suggest that estradiol acts directly on dopamine-producing neurons of the tuberoinfundibular system and incertohypothalamic system.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)