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Science 24 February 1984:
Vol. 223. no. 4638, pp. 822 - 825
DOI: 10.1126/science.6695184
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Articles

Science, Vol 223, Issue 4638, 822-825
Copyright © 1984 by American Association for the Advancement of Science

articles

Microdifferential holography and the polysarcomeric unit of activation of skeletal muscle

M Sharnoff, TH Karcher, and LP Brehm

Unbalanced holographic difference images of contracting skeletal muscle fibers reveal that activation affects the amplitude of the light scattered by individual myofibrils. The results suggest that the unit of activation is not the sarcomeric structural unit, but a monomyofibrillar segment containing 20 to 40 contiguous sarcomeres.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)