Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 24 February 1984:
Vol. 223. no. 4638, pp. 820 - 822
DOI: 10.1126/science.6538050
Prev | Table of Contents | Next

Articles

Science, Vol 223, Issue 4638, 820-822
Copyright © 1984 by American Association for the Advancement of Science

articles

Cardiac atria of BIO 14.6 hamsters are deficient in natriuretic factor

JE Chimoskey, WS Spielman, MA Brandt, and Heidemann SR

The hearts of 220-day-old hamsters of the BIO 14.6 strain are deficient in atrial natriuretic factor; saline extracts of atria produce one-third the natriuretic and diuretic effects of extracts of atria from age-matched normal hamsters. BIO 14.6 hamsters are known to develop congestive heart failure with edema when they are about 200 days old, and the venous congestion and edema are preventable by parabiosis with normal hamsters. The humoral mediator, the deficiency of which causes venous congestion and edema in BIO 14.6 hamsters, may be atrial natriuretic factor.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Alternate Circulating Pro-B-Type Natriuretic Peptide and B-Type Natriuretic Peptide Forms in the General Population.
C. S.P. Lam, J. C. Burnett Jr, L. Costello-Boerrigter, R. J. Rodeheffer, and M. M. Redfield (2007)
J. Am. Coll. Cardiol. 49, 1193-1202
   Abstract »    Full Text »    PDF »
Atrial natriuretic peptide elevation in congestive heart failure in the human.
J. Burnett Jr, P. Kao, D. Hu, D. Heser, D Heublein, J. Granger, T. Opgenorth, and G. Reeder (1986)
Science 231, 1145-1147
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)