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Science 27 January 1984:
Vol. 223. no. 4634, pp. 409 - 411
DOI: 10.1126/science.6691152
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Articles

Science, Vol 223, Issue 4634, 409-411
Copyright © 1984 by American Association for the Advancement of Science

articles

Prenatal exposure to carbon monoxide: learning and memory deficits

CF Mactutus and LD Fechter

Exposing pregnant rats to carbon monoxide (150 parts per million) produced only minor reductions in the birth weights of the pups and gave no evidence of overt teratogenesis. However, behavioral evaluation of learning and memory processes in a two-way avoidance task suggested a functional deficit in the central nervous system of the exposed offspring. Multiple dependent measures and specific control groups confirmed that this deficit was independent of nonassociative or motivational alterations.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Prenatal Exposure to a Low Concentration of Carbon Monoxide Disrupts Hippocampal Long-Term Potentiation in Rat Offspring.
G. Mereu, M. Cammalleri, M. Fà, W. Francesconi, P. Saba, M. Tattoli, L. Trabace, A. Vaccari, and V. Cuomo (2000)
J. Pharmacol. Exp. Ther. 294, 728-734
   Abstract »    Full Text »
Behavioral Teratology Comes to the Classroom.
Y. Brackbill (1987)
Topics in Early Childhood Special Education 6, 33-48
   Abstract »    PDF »


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