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Science 27 January 1984:
Vol. 223. no. 4634, pp. 407 - 409
DOI: 10.1126/science.6197755
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Articles

Science, Vol 223, Issue 4634, 407-409
Copyright © 1984 by American Association for the Advancement of Science

articles

Expression of glial fibrillary acidic protein in immature oligodendroglia

BH Choi and RC Kim

In the human fetal spinal cord at 15 to 16 weeks, glial fibrillary acidic protein (GFAP) was demonstrated within the cytoplasm and processes of cells having the cytological, ultrastructural, and immunocytochemical features of oligodendrocytes--including processes that extend into and contribute to the formation of myelin sheaths. By 17 to 18 weeks, however, GFAP immunoreactivity was no longer evident within such cells. Thus GFAP is expressed by myelin-forming oligodendroglia early in their development.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Morphologic and molecular genetic aspects of oligodendroglial neoplasms.
S. H. Bigner, B.K. A. Rasheed, R. Wiltshire, and R. E. McLendon (1999)
Neuro-oncol 1, 52-60
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