Science 18 November 1983: Vol. 222. no. 4625, pp. 771 - 778 DOI: 10.1126/science.6356358

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Wild-Type p53 Enhances Efficiency of Simian Virus 40 Large-T-Antigen-Induced Cellular Transformation.

A. Hermannstadter, C. Ziegler, M. Kuhl, W. Deppert, and G. V. Tolstonog (2009)
J. Virol. 83, 10106-10118
 |  Abstract »  |  Full Text »  |  PDF »

ERG Is a Megakaryocytic Oncogene.

S. Salek-Ardakani, G. Smooha, J. de Boer, N. J. Sebire, M. Morrow, L. Rainis, S. Lee, O. Williams, S. Izraeli, and H. J.M. Brady (2009)
Cancer Res. 69, 4665-4673
 |  Abstract »  |  Full Text »  |  PDF »

Cyclic AMP Selectively Uncouples Mitogen-Activated Protein Kinase Cascades from Activating Signals.

G. W. Pearson, S. Earnest, and M. H. Cobb (2006)
Mol. Cell. Biol. 26, 3039-3047
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Degradation of p53, Not Telomerase Activation, by E6 Is Required for Bypass of Crisis and Immortalization by Human Papillomavirus Type 16 E6/E7.

H. R. McMurray and D. J. McCance (2004)
J. Virol. 78, 5698-5706
 |  Abstract »  |  Full Text »  |  PDF »

Energetic basis for selective recognition of T{middle dot}G mismatched base pairs in DNA by imidazole-rich polyamides.

E. R. Lacy, B. Nguyen, M. Le, K. K. Cox, C. O'Hare, J. A. Hartley, M. Lee, and W. D. Wilson (2004)
Nucleic Acids Res. 32, 2000-2007
 |  Abstract »  |  Full Text »  |  PDF »

E{micro}-BRD2 transgenic mice develop B-cell lymphoma and leukemia.

R. J. Greenwald, J. R. Tumang, A. Sinha, N. Currier, R. D. Cardiff, T. L. Rothstein, D. V. Faller, and G. V. Denis (2004)
Blood 103, 1475-1484
 |  Abstract »  |  Full Text »  |  PDF »

Human Papillomavirus Type 16 E6 Activates TERT Gene Transcription through Induction of c-Myc and Release of USF-Mediated Repression.

H. R. McMurray and D. J. McCance (2003)
J. Virol. 77, 9852-9861
 |  Abstract »  |  Full Text »  |  PDF »

Proapoptotic BID is required for myeloid homeostasis and tumor suppression.

S. S. Zinkel, C. C. Ong, D. O. Ferguson, H. Iwasaki, K. Akashi, R. T. Bronson, J. L. Kutok, F. W. Alt, and S. J. Korsmeyer (2003)
Genes & Dev. 17, 229-239
 |  Abstract »  |  Full Text »  |  PDF »

A Ligand-inducible Epidermal Growth Factor Receptor/Anaplastic Lymphoma Kinase Chimera Promotes Mitogenesis and Transforming Properties in 3T3 Cells.

G. Piccinini, R. Bacchiocchi, M. Serresi, C. Vivani, S. Rossetti, C. Gennaretti, D. Carbonari, and F. Fazioli (2002)
J. Biol. Chem. 277, 22231-22239
 |  Abstract »  |  Full Text »  |  PDF »

Recognition of T{middle dot}G mismatched base pairs in DNA by stacked imidazole-containing polyamides: surface plasmon resonance and circular dichroism studies.

E. R. Lacy, K. K. Cox, W. D. Wilson, and M. Lee (2002)
Nucleic Acids Res. 30, 1834-1841
 |  Abstract »  |  Full Text »  |  PDF »

Stabilized {beta}-Catenin Immortalizes Colonic Epithelial Cells.

R. A. Wagenaar, H. C. Crawford, and L. M. Matrisian (2001)
Cancer Res. 61, 2097-2104
 |  Abstract »  |  Full Text »

Role of bcl-2 in Epstein-Barr Virus-Induced Malignant Conversion of Burkitt's Lymphoma Cell Line Akata.

J. Komano and K. Takada (2001)
J. Virol. 75, 1561-1564
 |  Abstract »  |  Full Text »

A Modest Reduction in c-Myc Expression Has Minimal Effects on Cell Growth and Apoptosis But Dramatically Reduces Susceptibility to Ras and Raf Transformation.

A. V. Bazarov, S. Adachi, S.-F. Li, M. K. Mateyak, S. Wei, and J. M. Sedivy (2001)
Cancer Res. 61, 1178-1186
 |  Abstract »  |  Full Text »

Molecular Biology of Burkitt's Lymphoma.

J. L. Hecht and J. C. Aster (2000)
J. Clin. Oncol. 18, 3707-3721
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis.

K. Inoue, R. Wen, J. E. Rehg, M. Adachi, J. L. Cleveland, M. F. Roussel, and C. J. Sherr (2000)
Genes & Dev. 14, 1797-1809
 |  Abstract »  |  Full Text »

Tumor progression and metastasis.

J. Yokota (2000)
Carcinogenesis 21, 497-503
 |  Abstract »  |  Full Text »  |  PDF »

Isolation of Transformation Suppressor Genes by cDNA Subtraction: Lumican Suppresses Transformation Induced by v-src and v-K-ras.

N. Yoshioka, H. Inoue, K. Nakanishi, K. Oka, M. Yutsudo, A. Yamashita, A. Hakura, and H. Nojima (2000)
J. Virol. 74, 1008-1013
 |  Abstract »  |  Full Text »

Oncogenic Role of Epstein-Barr Virus-Encoded RNAs in Burkitt's Lymphoma Cell Line Akata.

J. Komano, S. Maruo, K. Kurozumi, T. Oda, and K. Takada (1999)
J. Virol. 73, 9827-9831
 |  Abstract »  |  Full Text »

Absence of Genetic Alteration at Codon 531 of the Human c-src Gene in 479 Advanced Colorectal Cancers from Japanese and Caucasian Patients.

Y. Daigo, Y. Furukawa, T. Kawasoe, H. Ishiguro, M. Fujita, S. Sugai, S. Nakamori, G.-J. Liefers, R. A. E. M. Tollenaar, C. J. H. van de Velde, et al. (1999)
Cancer Res. 59, 4222-4224
 |  Abstract »  |  Full Text »  |  PDF »

An in vitro model of the early genetic events in multistage carcinogenesis of malignant insulinoma.

M. Wrischer (1999)
Carcinogenesis 20, 1521-1528
 |  Abstract »  |  Full Text »  |  PDF »

Loss of the ARF Tumor Suppressor Reverses Premature Replicative Arrest but not Radiation Hypersensitivity Arising from Disabled Atm Function.

T. Kamijo, E. van de Kamp, M. J. Chong, F. Zindy, J. A. Diehl, C. J. Sherr, and P. J. McKinnon (1999)
Cancer Res. 59, 2464-2469
 |  Abstract »  |  Full Text »  |  PDF »

Dormant Tumor-Suppressor Pathways in Tumors.

S. J. Weintraub (1999)
Am. J. Respir. Cell Mol. Biol. 20, 541-542
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Mutant N-ras Induces Myeloproliferative Disorders and Apoptosis in Bone Marrow Repopulated Mice.

K.L. MacKenzie, A. Dolnikov, M. Millington, Y. Shounan, and G. Symonds (1999)
Blood 93, 2043-2056
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the pRb-Binding Regions of E1A Enables Efficient Transformation of Primary Epithelial Cells by v-src.

R. S. Fischer and M. P. Quinlan (1998)
J. Virol. 72, 2815-2824
 |  Abstract »  |  Full Text »  |  PDF »

Anchorage-Independent Transcription of the Cyclin A Gene Induced by the E7 Oncoprotein of Human Papillomavirus Type 16.

A. Schulze, B. Mannhardt, K. Zerfass-Thome, W. Zwerschke, and P. Jansen-Durr (1998)
J. Virol. 72, 2323-2334
 |  Abstract »  |  Full Text »  |  PDF »

Thyroid-Specific Expression of Cholera Toxin A1 Subunit Causes Thyroid Hyperplasia and Hyperthyroidism in Transgenic Mice.

M. A. Zeiger, M. Saji, Y. Gusev, W. H. Westra, Y. Takiyama, W. C. Dooley, L. D. Kohn, and M. A. Levine (1997)
Endocrinology 138, 3133-3140
 |  Abstract »  |  Full Text »  |  PDF »

A Tyrosine-Phosphorylated Protein of 140 kD Is Constitutively Associated With the Phosphotyrosine Binding Domain of Shc and the SH3 Domains of Grb2 in Acute Myeloid Leukemia Cells.

M. Jucker, C. A. Schiffer, and R. A. Feldman (1997)
Blood 89, 2024-2035
 |  Abstract »  |  Full Text »  |  PDF »

Differential Tolerance to DNA Polymerization by HIV-1 Reverse Transcriptase on N6 Adenine C10R and C10S Benzo[a]pyrene-7,8-dihydrodiol 9,10-Epoxide-adducted Templates.

P. Chary, C. M. Harris, T. M. Harris, and R. S. Lloyd (1997)
J. Biol. Chem. 272, 5805-5813
 |  Abstract »  |  Full Text »  |  PDF »

Tumor suppressor genes.

R. Weinberg (1991)
Science 254, 1138-1146
 |  Abstract »  |  PDF »

Ubiquitin Hybrid Protein Gene Expression During Human Colon Cancer Progression.

K.-i. Mafune, J. M. Wong, R. J. Staniunas, M. L. Lu, T. S. Ravikumar, L. B. Chen, and G. D. Steele Jr (1991)
Arch Surg 126, 462-466
 |  Abstract »  |  PDF »

Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development..

D Martin-Zanca, M Barbacid, and L F Parada (1990)
Genes & Dev. 4, 683-694
 |  Abstract »  |  PDF »

cHa-ras Proto-oncogene: Amplification and Overexpression in UV-B-Induced Mouse Skin Papillomas and Carcinomas.

Z. Husain, Q. Yang, and D. K. Biswas (1990)
Arch Dermatol 126, 324-330
 |  Abstract »  |  PDF »

Environmental Exposures in Cytogenetically Defined Subsets of Acute Nonlymphocytic Leukemia.

M. M. Crane, M. J. Keating, J. M. Trujillo, D. R. Labarthe, and R. F. Frankowski (1989)
JAMA 262, 634-639
 |  Abstract »  |  PDF »

Allelic Loss in Colorectal Carcinoma.

S. E. Kern, E. R. Fearon, K. W. F. Tersmette, J. P. Enterline, M. Leppert, Y. Nakamura, R. White, B. Vogelstein, and S. R. Hamilton (1989)
JAMA 261, 3099-3103
 |  Abstract »  |  PDF »

Genetic rearrangements and gene amplification in Escherichia coli: DNA sequences at the junctures of amplified gene fusions..

S K Whoriskey, V H Nghiem, P M Leong, J M Masson, and J H Miller (1987)
Genes & Dev. 1, 227-237
 |  Abstract »  |  PDF »

Identification of an amplified, highly expressed gene in a human glioma.

K. Kinzler, S. Bigner, D. Bigner, J. Trent, M. Law, S. O'Brien, A. Wong, and B Vogelstein (1987)
Science 236, 70-73
 |  Abstract »  |  PDF »

The molecular genetics of cancer.

J. Bishop (1987)
Science 235, 305-311
 |  Abstract »  |  PDF »

Gene amplification of c-myc and N-myc in small cell carcinoma of the lung.

A. Wong, J. Ruppert, J Eggleston, Hamilton SR, S. Baylin, and B Vogelstein (1986)
Science 233, 461-464
 |  Abstract »  |  PDF »

Characterization of Two New Human Oncogenes.

C. Birchmeier, D. Young, and M. Wigler (1986)
Cold Spring Harb Symp Quant Biol 51, 993-1000
 |  Abstract »  |  PDF »

The action of oncogenes in the cytoplasm and nucleus.

R. Weinberg (1985)
Science 230, 770-776
 |  Abstract »  |  PDF »

Functional relation between HTLV-II x and adenovirus E1A proteins in transcriptional activation.

I. Chen, A. Cann, N. Shah, and R. Gaynor (1985)
Science 230, 570-573
 |  Abstract »  |  PDF »

Activated proto-onc genes: sufficient or necessary for cancer?.

P. Duesberg (1985)
Science 228, 669-677
 |  Abstract »  |  PDF »

The following were presented at the joint meeting of the British Toxicology Society and British Pharmacological Society, London, 17-19 December 1984: John Barnes Lecture.

J. Cairns (1985)
Human and Experimental Toxicology 4, 341-343
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Hypomethylation of DNA from benign and malignant human colon neoplasms.

S. Goelz, B Vogelstein, Hamilton SR, and A. Feinberg (1985)
Science 228, 187-190
 |  Abstract »  |  PDF »

Location of the c-yes gene on the human chromosome and its expression in various tissues.

K Semba, Y Yamanashi, M Nishizawa, J Sukegawa, M Yoshida, M Sasaki, T Yamamoto, and K Toyoshima (1985)
Science 227, 1038-1040
 |  Abstract »  |  PDF »

Autoimmunity and increased c-myb transcription.

J. Mountz, A. Steinberg, D. Klinman, H. Smith, and J. Mushinski (1984)
Science 226, 1087-1089
 |  Abstract »  |  PDF »

Detection of high molecular weight forms of platelet-derived growth factor by sequence-specific antisera.

H. Niman, R. Houghten, and D. Bowen-Pope (1984)
Science 226, 701-703
 |  Abstract »  |  PDF »

Amplification of the c-myb oncogene in a case of human acute myelogenous leukemia.

P. Pelicci, L Lanfrancone, M. Brathwaite, Wolman SR, and R Dalla-Favera (1984)
Science 224, 1117-1121
 |  Abstract »  |  PDF »

Retinoblastoma: clues to human oncogenesis.

A. Murphree and W. Benedict (1984)
Science 223, 1028-1033
 |  Abstract »  |  PDF »

What do oncogenes do?.

J. Marx (1984)
Science 223, 673-674
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Translocations among antibody genes in human cancer.

P Leder, J Battey, G Lenoir, C Moulding, W Murphy, H Potter, T Stewart, and R Taub (1983)
Science 222, 765-771
 |  Abstract »  |  PDF »

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