Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 18 November 1983:
Vol. 222. no. 4625, pp. 755 - 765
DOI: 10.1126/science.6314502
Prev | Table of Contents | Next

Articles

Science, Vol 222, Issue 4625, 755-765
Copyright © 1983 by American Association for the Advancement of Science

articles

Insertion sequence duplication in transpositional recombination

TA Weinert, NA Schaus, and ND Grindley

Insertion sequences (IS) are discrete segments of DNA that can transpose from one genomic site to another and promote genetic rearrangements. A question that is central to understanding the mechanism of transpositional recombination is whether genetic rearrangements are accompanied by duplication of the IS that promotes them. Analysis of adjacent deletions mediated by IS903 provides the strongest evidence to date than any IS-mediated transpositional recombination can occur by an efficient replicative mechanism.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Translocation of transposition-deficient (TndPKLH2-like) transposons in the natural environment: mechanistic insights from the study of adjacent DNA sequences.
G. Kholodii, S. Mindlin, Z. Gorlenko, M. Petrova, J. Hobman, and V. Nikiforov (2004)
Microbiology 150, 979-992
   Abstract »    Full Text »    PDF »
Mu-Like Prophage in Serogroup B Neisseria meningitidis Coding for Surface-Exposed Antigens.
V. Masignani, M. M. Giuliani, H. Tettelin, M. Comanducci, R. Rappuoli, and V. Scarlato (2001)
Infect. Immun. 69, 2580-2588
   Abstract »    Full Text »    PDF »
A Rare 920-Kilobase Chromosomal Inversion Mediated by IS1 Transposition Causes Constitutive Expression of the yiaK-S Operon for Carbohydrate Utilization in Escherichia coli.
J. Badia, E. Ibanez, M. Sabate, L. Baldoma, and J. Aguilar (1998)
J. Biol. Chem. 273, 8376-8381
   Abstract »    Full Text »    PDF »
cis-acting DNA sequence requirements for P-element transposition..
M C Mullins, D C Rio, and G M Rubin (1989)
Genes & Dev. 3, 729-738
   Abstract »    PDF »
Replicative and Conservative Transpositional Recombination of Insertion Sequences.
T.A. Weinert, K.M. Derbyshire, F.M. Hughson, and N.D.F. Grindley (1984)
Cold Spring Harb Symp Quant Biol 49, 251-260
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)