Science 23 September 1983: Vol. 221. no. 4617, pp. 1256 - 1264 DOI: 10.1126/science.6351251

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Articles

A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis.

J. S. Park, L. K. Sharma, H. Li, R. Xiang, D. Holstein, J. Wu, J. Lechleiter, S. L. Naylor, J. J. Deng, J. Lu, et al. (2009)
Hum. Mol. Genet. 18, 1578-1589
 |  Abstract »  |  Full Text »  |  PDF »

Global Analysis of Protein Damage by the Lipid Electrophile 4-Hydroxy-2-nonenal.

S. G. Codreanu, B. Zhang, S. M. Sobecki, D. D. Billheimer, and D. C. Liebler (2009)
Mol. Cell. Proteomics 8, 670-680
 |  Abstract »  |  Full Text »  |  PDF »

Vitamins E and C in the Prevention of Prostate and Total Cancer in Men: The Physicians' Health Study II Randomized Controlled Trial.

J. M. Gaziano, R. J. Glynn, W. G. Christen, T. Kurth, C. Belanger, J. MacFadyen, V. Bubes, J. E. Manson, H. D. Sesso, and J. E. Buring (2009)
JAMA 301, 52-62
 |  Abstract »  |  Full Text »  |  PDF »

Vitamins C and E and Beta Carotene Supplementation and Cancer Risk: A Randomized Controlled Trial.

J. Lin, N. R. Cook, C. Albert, E. Zaharris, J. M. Gaziano, M. Van Denburgh, J. E. Buring, and J. E. Manson (2009)
J Natl Cancer Inst 101, 14-23
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TIP30 Induces Apoptosis under Oxidative Stress through Stabilization of p53 Messenger RNA in Human Hepatocellular Carcinoma.

J. Zhao, J. Chen, B. Lu, L. Dong, H. Wang, C. Bi, G. Wu, H. Guo, M. Wu, and Y. Guo (2008)
Cancer Res. 68, 4133-4141
 |  Abstract »  |  Full Text »  |  PDF »

Tempol Protects against Oxidative Damage and Delays Epithelial Tumor Onset in Fanconi Anemia Mice.

Q.-S. Zhang, L. Eaton, E. R. Snyder, S. Houghtaling, J. B. Mitchell, M. Finegold, C. Van Waes, and M. Grompe (2008)
Cancer Res. 68, 1601-1608
 |  Abstract »  |  Full Text »  |  PDF »

Quercetin 3-Glucoside Protects Neuroblastoma (SH-SY5Y) Cells in Vitro against Oxidative Damage by Inducing Sterol Regulatory Element-binding Protein-2-mediated Cholesterol Biosynthesis.

R. Soundararajan, A. D. Wishart, H. P. V. Rupasinghe, M. Arcellana-Panlilio, C. M. Nelson, M. Mayne, and G. S. Robertson (2008)
J. Biol. Chem. 283, 2231-2245
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Protection against Oxidative Stress-induced Hepatic Injury by Intracellular Type II Platelet-activating Factor Acetylhydrolase by Metabolism of Oxidized Phospholipids in Vivo.

N. Kono, T. Inoue, Y. Yoshida, H. Sato, T. Matsusue, H. Itabe, E. Niki, J. Aoki, and H. Arai (2008)
J. Biol. Chem. 283, 1628-1636
 |  Abstract »  |  Full Text »  |  PDF »

Coordination of Steps in Single-nucleotide Base Excision Repair Mediated by Apurinic/Apyrimidinic Endonuclease 1 and DNA Polymerase beta.

Y. Liu, R. Prasad, W. A. Beard, P. S. Kedar, E. W. Hou, D. D. Shock, and S. H. Wilson (2007)
J. Biol. Chem. 282, 13532-13541
 |  Abstract »  |  Full Text »  |  PDF »

Effect of the Carotenoid-Producing Alga, Dunaliella bardawil, on CCl4-Induced Toxicity in Rats.

A. Vanitha, K. N. Chidambara Murthy, V. Kumar, G. Sakthivelu, J. M. Veigas, P. Saibaba, and G. A. Ravishankar (2007)
International Journal of Toxicology 26, 159-167
 |  Abstract »  |  Full Text »  |  PDF »

Recognition of Nucleotide Analogs Containing the 7,8-Dihydro-8-oxo Structure by the Human MTH1 Protein.

H. Kamiya, C. Cadena-Amaro, L. Dugue, H. Yakushiji, N. Minakawa, A. Matsuda, S. Pochet, Y. Nakabeppu, and H. Harashima (2006)
J. Biochem. 140, 843-849
 |  Abstract »  |  Full Text »  |  PDF »

Genetic and Cellular Toxicology of Dental Resin Monomers.

H. Schweikl, G. Spagnuolo, and G. Schmalz (2006)
Journal of Dental Research 85, 870-877
 |  Abstract »  |  Full Text »  |  PDF »

Reactive Species and Antioxidants. Redox Biology Is a Fundamental Theme of Aerobic Life.

B. Halliwell (2006)
Plant Physiology 141, 312-322
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8-Isoprostane F2{alpha} excretion is reduced in women by increased vegetable and fruit intake.

H. J Thompson, J. Heimendinger, S. Sedlacek, A. Haegele, A. Diker, C. O'Neill, B. Meinecke, P. Wolfe, Z. Zhu, and W. Jiang (2005)
Am. J. Clinical Nutrition 82, 768-776
 |  Abstract »  |  Full Text »  |  PDF »

Loss-of-Function of Nkx3.1 Promotes Increased Oxidative Damage in Prostate Carcinogenesis.

X. Ouyang, T. L. DeWeese, W. G. Nelson, and C. Abate-Shen (2005)
Cancer Res. 65, 6773-6779
 |  Abstract »  |  Full Text »  |  PDF »

Identification of the Major Urinary Metabolite of the Highly Reactive Cyclopentenone Isoprostane 15-A2t-Isoprostane in Vivo.

G. L. Milne, L. Gao, A. Porta, G. Zanoni, G. Vidari, and J. D. Morrow (2005)
J. Biol. Chem. 280, 25178-25184
 |  Abstract »  |  Full Text »  |  PDF »

Specific Antibody Modulates Absorptive Transport and Metabolic Activation of Benzo[a]pyrene across Caco-2 Monolayers.

S. S. De Buck, P. Augustijns, and C. P. Muller (2005)
J. Pharmacol. Exp. Ther. 313, 640-646
 |  Abstract »  |  Full Text »  |  PDF »

Effects of exercise and diet on chronic disease.

C. K. Roberts and R. J. Barnard (2005)
J Appl Physiol 98, 3-30
 |  Abstract »  |  Full Text »  |  PDF »

Anti-inflammatory Effects of Aronia Extract on Rat Endotoxin-Induced Uveitis.

K. Ohgami, I. Ilieva, K. Shiratori, Y. Koyama, X.-H. Jin, K. Yoshida, S. Kase, N. Kitaichi, Y. Suzuki, T. Tanaka, et al. (2005)
Invest. Ophthalmol. Vis. Sci. 46, 275-281
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Prevention of Cancer Through Lifestyle Changes.

R. J. Barnard (2004)
Evid. Based Complement. Altern. Med. 1, 233-239
 |  Abstract »  |  Full Text »  |  PDF »

Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk.

E.M.J. van der Logt, S.M. Bergevoet, H.M.J. Roelofs, Z. van Hooijdonk, R.H.M. te Morsche, T. Wobbes, J.B. de Kok, F.M. Nagengast, and W.H.M. Peters (2004)
Carcinogenesis 25, 2407-2415
 |  Abstract »  |  Full Text »  |  PDF »

The SU.VI.MAX Study: A Randomized, Placebo-Controlled Trial of the Health Effects of Antioxidant Vitamins and Minerals.

S. Hercberg, P. Galan, P. Preziosi, S. Bertrais, L. Mennen, D. Malvy, A.-M. Roussel, A. Favier, and S. Briancon (2004)
Arch Intern Med 164, 2335-2342
 |  Abstract »  |  Full Text »  |  PDF »

Nitric Oxide as an Endogenous Mutagen for Sendai Virus without Antiviral Activity.

J. Yoshitake, T. Akaike, T. Akuta, F. Tamura, T. Ogura, H. Esumi, and H. Maeda (2004)
J. Virol. 78, 8709-8719
 |  Abstract »  |  Full Text »  |  PDF »

Lipid peroxidation induced by DHA enrichment modifies paracellular permeability in Caco-2 cells: protective role of taurine.

S. Roig-Perez, F. Guardiola, M. Moreto, and R. Ferrer (2004)
J. Lipid Res. 45, 1418-1428
 |  Abstract »  |  Full Text »  |  PDF »

Selenium and Lung Cancer: A Quantitative Analysis of Heterogeneity in the Current Epidemiological Literature.

H. Zhuo, A. H. Smith, and C. Steinmaus (2004)
Cancer Epidemiol. Biomarkers Prev. 13, 771-778
 |  Abstract »  |  Full Text »  |  PDF »

Protective effects of indole-3-carbinol on cyclophosphamide-induced clastogenecity in mouse bone marrow cells.

Y. Shukla, B. Srivastava, A. Arora, and L K. Chauhan (2004)
Human and Experimental Toxicology 23, 245-250
 |  Abstract »  |  PDF »

Total Equivalent of Reactive Chemicals in 142 Human Food Items Is Highly Variable Within and Between Major Food Groups.

M. He, K. Openo, M. McCullough, and D. P. Jones (2004)
J. Nutr. 134, 1114-1119
 |  Abstract »  |  Full Text »  |  PDF »

p53-Induced Up-Regulation of MnSOD and GPx but not Catalase Increases Oxidative Stress and Apoptosis.

S. P. Hussain, P. Amstad, P. He, A. Robles, S. Lupold, I. Kaneko, M. Ichimiya, S. Sengupta, L. Mechanic, S. Okamura, et al. (2004)
Cancer Res. 64, 2350-2356
 |  Abstract »  |  Full Text »  |  PDF »

p53-Mediated Oxidative Stress and Apoptosis: S. PERWEZ HUSSAIN, PAUL AMSTAD, PEIJUN HE, ANA ROBLES, SHAWN LUPOLD, SAGAR SENGUPTA, MASATO ICHIMIYA, SHU OKAMURA, MATHEW MOAKE, KATHLEEN FORRESTER, AND CURTIS C. HARRIS, Laboratory of Human Carcinogenesis, National Cancer Institute, NIH, Bethesda, Maryland 20892.

(2004)
Toxicol Pathol 32, 163-164
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Nutritional risk predictors of {beta} cell autoimmunity and type 1 diabetes at a young age.

S. M Virtanen and M. Knip (2003)
Am. J. Clinical Nutrition 78, 1053-1067
 |  Abstract »  |  Full Text »  |  PDF »

Fatty Acids and Risk of Prostate Cancer in a Nested Case-Control Study in Male Smokers.

S. Mannisto, P. Pietinen, M. J. Virtanen, I. Salminen, D. Albanes, E. Giovannucci, and J. Virtamo (2003)
Cancer Epidemiol. Biomarkers Prev. 12, 1422-1428
 |  Abstract »  |  Full Text »  |  PDF »

Characterization and Inheritance of the Anthocyanin fruit (Aft) Tomato.

C. M. Jones, P. Mes, and J. R. Myers (2003)
J. Hered. 94, 449-456
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New Paraoxonase 1 Polymorphism I102V and the Risk of Prostate Cancer in Finnish Men.

M. Marchesani, A. Hakkarainen, T.-P. Tuomainen, J. Kaikkonen, E. Pukkala, P. Uimari, E. Seppala, M. Matikainen, O.-P. Kallioniemi, J. Schleutker, et al. (2003)
J Natl Cancer Inst 95, 812-818
 |  Abstract »  |  Full Text »  |  PDF »

Mutagenic effects of 2-hydroxy-dATP on replication in a HeLa extract: induction of substitution and deletion mutations.

K. Satou, H. Harashima, and H. Kamiya (2003)
Nucleic Acids Res. 31, 2570-2575
 |  Abstract »  |  Full Text »  |  PDF »

Does Heme Oxygenase-1 Have a Role in Caco-2 Cell Cycle Progression?.

A. Uc and B. E. Britigan (2003)
Experimental Biology and Medicine 228, 590-595
 |  Abstract »  |  Full Text »  |  PDF »

Nigella sativa (black cumin) ameliorates potassium bromate-induced early events of carcinogenesis: diminution of oxidative stress.

N. Khan, S. Sharma, and S. Sultana (2003)
Human and Experimental Toxicology 22, 193-203
 |  Abstract »  |  PDF »

Mutagenic potentials of damaged nucleic acids produced by reactive oxygen/nitrogen species: approaches using synthetic oligonucleotides and nucleotides: SURVEY AND SUMMARY.

H. Kamiya (2003)
Nucleic Acids Res. 31, 517-531
 |  Abstract »  |  Full Text »  |  PDF »

Gape coloration reliably reflects immunocompetence of barn swallow (Hirundo rustica) nestlings.

N. Saino, R. Ambrosini, R. Martinelli, P. Ninni, and A. P. Moller (2003)
Behav. Ecol. 14, 16-22
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Nutritional and lifestyle determinants of DNA oxidative damage: a study in a Mediterranean population.

L. Giovannelli, C. Saieva, G. Masala, G. Testa, S. Salvini, V. Pitozzi, E. Riboli, P. Dolara, and D. Palli (2002)
Carcinogenesis 23, 1483-1489
 |  Abstract »  |  Full Text »  |  PDF »

Application of Single-Cell Gel Electrophoresis (Comet) Assay for Assessing Levels of DNA Damage in Canine and Feline Leukocytes.

P. R. Heaton, R. Ransley, C. J. Charlton, S. J. Mann, J. Stevenson, B. H. E. Smith, J. M. Rawlings, and E. J. Harper (2002)
J. Nutr. 132, 1598S-1603
 |  Abstract »  |  Full Text »  |  PDF »

Role of Dietary Antioxidants to Protect against DNA Damage in Adult Dogs.

P. R. Heaton, C. F. Reed, S. J. Mann, R. Ransley, J. Stevenson, C. J. Charlton, B. H. E. Smith, E. J. Harper, and J. M. Rawlings (2002)
J. Nutr. 132, 1720S-1724
 |  Abstract »  |  Full Text »  |  PDF »

Effects of a Guanine-derived Formamidopyrimidine Lesion on DNA Replication. TRANSLESION DNA SYNTHESIS, NUCLEOTIDE INSERTION, AND EXTENSION KINETICS.

K. Asagoshi, H. Terato, Y. Ohyama, and H. Ide (2002)
J. Biol. Chem. 277, 14589-14597
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative DNA Damage in Prostate Cancer Patients Consuming Tomato Sauce-Based Entrees as a Whole-Food Intervention.

L. Chen, M. Stacewicz-Sapuntzakis, C. Duncan, R. Sharifi, L. Ghosh, R. v. Breemen, D. Ashton, and P. E. Bowen (2001)
J Natl Cancer Inst 93, 1872-1879
 |  Abstract »  |  Full Text »  |  PDF »

Structure-dependent reactivity of oxyfunctionalized acetophenones in the photooxidation of DNA: base oxidation and strand breaks through photolytic radical formation (spin trapping, EPR spectroscopy, transient kinetics) versus photosensitization (electron transfer, hydrogen-atom abstraction).

W. Adam, M. A. Arnold, W. M. Nau, U. Pischel, and C. R. Saha-Moller (2001)
Nucleic Acids Res. 29, 4955-4962
 |  Abstract »  |  Full Text »  |  PDF »

Differential DNA recognition and glycosylase activity of the native human MutY homolog (hMYH) and recombinant hMYH expressed in bacteria.

Y. Gu and A-L. Lu (2001)
Nucleic Acids Res. 29, 2666-2674
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative stress promotes the development of transformation: involvement of a potent mutagenic lipid peroxidation product, acrolein.

W. Takabe, E. Niki, K. Uchida, S. Yamada, K. Satoh, and N. Noguchi (2001)
Carcinogenesis 22, 935-941
 |  Abstract »  |  Full Text »  |  PDF »

Charge transport through DNA four-way junctions.

D. T. Odom, E. A. Dill, and J. K. Barton (2001)
Nucleic Acids Res. 29, 2026-2033
 |  Abstract »  |  Full Text »  |  PDF »

The Cap 'n' Collar Basic Leucine Zipper Transcription Factor Nrf2 (NF-E2 p45-related Factor 2) Controls Both Constitutive and Inducible Expression of Intestinal Detoxification and Glutathione Biosynthetic Enzymes.

M. McMahon, K. Itoh, M. Yamamoto, S. A. Chanas, C. J. Henderson, L. I. McLellan, C. R. Wolf, C. Cavin, and J. D. Hayes (2001)
Cancer Res. 61, 3299-3307
 |  Abstract »  |  Full Text »

Chemoprevention: Increased potential to bear fruit.

C. R. Wolf (2001)
PNAS 98, 2941-2943
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Glutathione S-Transferase M1, M3, P1, and T1 Genetic Polymorphisms and Susceptibility to Breast Cancer.

K. Mitrunen, N. Jourenkova, V. Kataja, M. Eskelinen, V.-M. Kosma, S. Benhamou, H. Vainio, M. Uusitupa, and A. Hirvonen (2001)
Cancer Epidemiol. Biomarkers Prev. 10, 229-236
 |  Abstract »  |  Full Text »

Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2-hydroxy-ATP.

K. Fujikawa, H. Kamiya, H. Yakushiji, Y. Nakabeppu, and H. Kasai (2001)
Nucleic Acids Res. 29, 449-454
 |  Abstract »  |  Full Text »  |  PDF »

Lipid hydroperoxide-induced apoptosis in human colonic CaCo-2 cells is associated with an early loss of cellular redox balance.

T.-G. WANG, Y. GOTOH, M. H. JENNINGS, C. A. RHOADS, and T. Y. AW (2000)
FASEB J 14, 1567-1576
 |  Abstract »  |  Full Text »

Green Tea and Skin.

S. K. Katiyar, N. Ahmad, and H. Mukhtar (2000)
Arch Dermatol 136, 989-994
 |  Abstract »  |  Full Text »  |  PDF »

Chapter 7: Molecular Epidemiology of Genetic Polymorphisms in Estrogen Metabolizing Enzymes in Human Breast Cancer.

P. A. Thompson and C. Ambrosone (2000)
J Natl Cancer Inst Monographs 2000, 125-134
 |  Abstract »  |  Full Text »  |  PDF »

In vitro DNA synthesis opposite oxazolone and repair of this DNA damage using modified oligonucleotides.

V. Duarte, D. Gasparutto, M. Jaquinod, and J. Cadet (2000)
Nucleic Acids Res. 28, 1555-1563
 |  Abstract »  |  Full Text »  |  PDF »

2-Hydroxy-dATP is incorporated opposite G by Escherichia coli DNA polymerase III resulting in high mutagenicity.

H. Kamiya and H. Kasai (2000)
Nucleic Acids Res. 28, 1640-1646
 |  Abstract »  |  Full Text »  |  PDF »

Glutathione S-Transferase in Mucus of Rat Small Intestine.

P. S. Samiec, L. J. Dahm, and D. P. Jones (2000)
Toxicol. Sci. 54, 52-59
 |  Abstract »  |  Full Text »  |  PDF »

Spontaneous and osmium tetroxide-induced mutagenesis in an Escherichia coli strain deficient in both endonuclease III and endonuclease VIII.

T. Najrana, Y. Saito, F. Uraki, K. Kubo, and K. Yamamoto (2000)
Mutagenesis 15, 121-125
 |  Abstract »  |  Full Text »  |  PDF »

Frequencies of hprt- mutations and bcl-2 translocations in circulating human lymphocytes are correlated with United Kingdom sunlight records.

G. Bentham, A. M. Wolfreys, Y. Liu, G. Cortopassi, M. H.L. Green, C. F. Arlett, and J. Cole (1999)
Mutagenesis 14, 527-532
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Molecular and cellular responses to oxidative stress and changes in oxidation-reduction imbalance in the intestine.

T. Y. Aw (1999)
Am. J. Clinical Nutrition 70, 557-565
 |  Abstract »  |  Full Text »  |  PDF »

Modifying effects of a flavonoid morin on azoxymethane-induced large bowel tumorigenesis in rats.

T. Tanaka, K. Kawabata, M. Kakumoto, H. Makita, J. Ushida, S. Honjo, A. Hara, H. Tsuda, and H. Mori (1999)
Carcinogenesis 20, 1477-1484
 |  Abstract »  |  Full Text »  |  PDF »

The Oxidized Forms of dATP Are Substrates for the Human MutT Homologue, the hMTH1 Protein.

K. Fujikawa, H. Kamiya, H. Yakushiji, Y. Fujii, Y. Nakabeppu, and H. Kasai (1999)
J. Biol. Chem. 274, 18201-18205
 |  Abstract »  |  Full Text »  |  PDF »

Environmental factors as regulators and effectors of multistep carcinogenesis.

T. Minamoto, M. Mai, and Z.'e. Ronai (1999)
Carcinogenesis 20, 519-527
 |  Abstract »  |  Full Text »  |  PDF »

Manganese Superoxide Dismutase (MnSOD) Genetic Polymorphisms, Dietary Antioxidants, and Risk of Breast Cancer.

C. B. Ambrosone, J. L. Freudenheim, P. A. Thompson, E. Bowman, J. E. Vena, J. R. Marshall, S. Graham, R. Laughlin, T. Nemoto, and P. G. Shields (1999)
Cancer Res. 59, 602-606
 |  Abstract »  |  Full Text »  |  PDF »

Glutathione-S-transferase (GSTM1) Genetic Polymorphisms Do Not Affect Human Breast Cancer Risk, Regardless of Dietary Antioxidants.

C. B. Ambrosone, B. F. Coles, J. L. Freudenheim, and P. G. Shields (1999)
J. Nutr. 129, 565
 |  Abstract »  |  Full Text »  |  PDF »

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain.

K. Itoh, N. Wakabayashi, Y. Katoh, T. Ishii, K. Igarashi, J. D. Engel, and M. Yamamoto (1999)
Genes & Dev. 13, 76-86
 |  Abstract »  |  Full Text »

Potential of Escherichia coli GTP Cyclohydrolase II for Hydrolyzing 8-Oxo-dGTP, a Mutagenic Substrate for DNA Synthesis.

M. Kobayashi, Y. Ohara-Nemoto, M. Kaneko, H. Hayakawa, M. Sekiguchi, and K. Yamamoto (1998)
J. Biol. Chem. 273, 26394-26399
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative DNA damage measured in human lymphocytes: large differences between sexes and between countries, and correlations with heart disease mortality rates.

A. R. Collins, C. M. Gedik, B. Olmedilla, S. Southon, and M. Bellizzi (1998)
FASEB J 12, 1397-1400
 |  Abstract »  |  Full Text »

Evidence that the E2-isoprostane, 15-E2t-isoprostane (8-iso-prostaglandin E2) is formed in vivo.

J. D. Morrow, J. Scruggs, Y. Chen, W. E. Zackert, and L. J. R. II (1998)
J. Lipid Res. 39, 1589-1593
 |  Abstract »  |  Full Text »

Induction of Chromosomal Gene Mutations in Escherichia coli by Direct Incorporation of Oxidatively Damaged Nucleotides. NEW EVALUATION METHOD FOR MUTAGENESIS BY DAMAGED DNA PRECURSORS IN VIVO.

M. Inoue, H. Kamiya, K. Fujikawa, Y. Ootsuyama, N. Murata-Kamiya, T. Osaki, K. Yasumoto, and H. Kasai (1998)
J. Biol. Chem. 273, 11069-11074
 |  Abstract »  |  Full Text »  |  PDF »

Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals.

C. V. Ramana, I. Boldogh, T. Izumi, and S. Mitra (1998)
PNAS 95, 5061-5066
 |  Abstract »  |  Full Text »  |  PDF »

Chronic hypoxia alters glucose utilization during GSH-dependent detoxication in rat small intestine.

T. S. Legrand and T. Y. Aw (1998)
Am J Physiol Gastrointest Liver Physiol 274, G376-G384
 |  Abstract »  |  Full Text »  |  PDF »

Suppressive effect of oestradiol on chemical hepatocarcinogenesis in rats.

I Shimizu, M Yasuda, Y Mizobuchi, Y-R Ma, F Liu, M Shiba, T Horie, and S Ito (1998)
Gut 42, 112-119
 |  Abstract »  |  Full Text »  |  PDF »

Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine.

B. Hang, B. Singer, G. P. Margison, and R. H. Elder (1997)
PNAS 94, 12869-12874
 |  Abstract »  |  Full Text »  |  PDF »

Selective Induction of Heparin-binding Epidermal Growth Factor-like Growth Factor by Methylglyoxal and 3-Deoxyglucosone in Rat Aortic Smooth Muscle Cells. THE INVOLVEMENT OF REACTIVE OXYGEN SPECIES FORMATION AND A POSSIBLE IMPLICATION FOR ATHEROGENESIS IN DIABETES.

W. Che, M. Asahi, M. Takahashi, H. Kaneto, A. Okado, S. Higashiyama, and N. Taniguchi (1997)
J. Biol. Chem. 272, 18453-18459
 |  Abstract »  |  Full Text »  |  PDF »

Evaluating chemical risks: results of a survey of the British Toxicology Society.

P. Slovic, T. Malmfors, C. Mertz, N. Neil, and I. F. Purchase (1997)
Human and Experimental Toxicology 16, 289-304
 |  Abstract »  |  PDF »

The Domains of Mammalian Base Excision Repair Enzyme N-Methylpurine-DNA Glycosylase. INTERACTION, CONFORMATIONAL CHANGE, AND ROLE IN DNA BINDING AND DAMAGE RECOGNITION.

R. Roy, A. Kumar, J. C. Lee, and S. Mitra (1996)
J. Biol. Chem. 271, 23690-23697
 |  Abstract »  |  Full Text »  |  PDF »

Nonenzymatic Free Radical-catalyzed Generation of Thromboxane-like Compounds (Isothromboxanes) in Vivo.

J. D. Morrow, J. A. Awad, A. Wu, W. E. Zackert, V. C. Daniel, and L. J. Roberts II (1996)
J. Biol. Chem. 271, 23185-23190
 |  Abstract »  |  Full Text »  |  PDF »

Identification of the Major Urinary Metabolite of the F2-isoprostane 8-Iso-prostaglandin F2alpha in Humans.

L. J. Roberts II, K. P. Moore, W. E. Zackert, J. A. Oates, and J. D. Morrow (1996)
J. Biol. Chem. 271, 20617-20620
 |  Abstract »  |  Full Text »  |  PDF »

Manganese Superoxide Dismutase Modulates Interleukin-1alpha Levels in HT-1080 Fibrosarcoma Cells.

J. A. Melendez and K. J.A. Davies (1996)
J. Biol. Chem. 271, 18898-18903
 |  Abstract »  |  Full Text »  |  PDF »

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L. H. Piette, J. J. McNamara, S. Premaratne, and W. Zhang (1996)
Angiology 47, 1-7
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W Willett, S Greenland, B MacMahon, D Trichopoulos, K Rothman, D Thomas, M Thun, and N Weiss (1995)
Science 269, 1325-1326
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Simultaneous Overexpression of Copper- and Zinc-containing Superoxide Dismutase and Catalase Retards Age-related Oxidative Damage and Increases Metabolic Potential in Drosophila melanogaster.

R. S. Sohal, A. Agarwal, S. Agarwal, and W. C. Orr (1995)
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Bionutrition and Oral Cancer in Humans.

C.O. Enwonwu and V.I. Meeks (1995)
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Cell cycle control and cancer.

L. Hartwell and M. Kastan (1994)
Science 266, 1821-1828
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Eugenol Triggers Different Pathobiological Effects on Human Oral Mucosal Fibroblasts 1.

J.H. Jeng, L.J. Hahn, E. Lu, Y. Wang, and M.Y.P. Kuo (1994)
Journal of Dental Research 73, 1050-1055
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Vitamins Regulate Gene Expression and Induce Differentiation and Growth Inhibition in Cancer Cells: Their Relevance in Cancer Prevention.

K. N. Prasad, J. Edwards-Prasad, S. Kumar, and A. Meyers (1993)
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How Much Cancer Is Occupationally Derived.

F.J.C. Roe (1993)
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Multistep carcinogenesis: a 1992 perspective.

T Sugimura (1992)
Science 258, 603-607
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Atomic structure of the DNA repair [4Fe-4S] enzyme endonuclease III.

C. Kuo, D. McRee, C. Fisher, S. O'Handley, R. Cunningham, and J. Tainer (1992)
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Review : Acetaldehyde and Formaldehyde: Is There a Cancer Risk for Man?.

F.J.C. Roe and D. Wood (1992)
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Transcriptional regulator of oxidative stress-inducible genes: direct activation by oxidation.

G Storz, L. Tartaglia, and B. Ames (1990)
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Yes, But Is It a Human Carcinogen?.

A. Furst (1990)
International Journal of Toxicology 9, 1-18
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Cultured Cells as a Screen for Novel Treatments of Alzheimer's Disease.

B. A. Malow, A. C. Baker, and J. P. Blass (1989)
Arch Neurol 46, 1201-1203
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Cigarette Smoking and Exposure to Passive Smoke Are Risk Factors for Cervical Cancer.

M. L. Slattery, L. M. Robison, K. L. Schuman, T. K. French, T. M. Abbott, J. C. Overall Jr, and J. W. Gardner (1989)
JAMA 261, 1593-1598
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The Role of Chemicals in the Etiology of Diabetes Mellitus.

G. L. Wilson and S. P. LeDoux (1989)
Toxicol Pathol 17, 357-363
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Carcinogenicity of Chemicals: The Weight of Evidence.

R.L. Carter (1988)
Human and Experimental Toxicology 7, 411-418
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Carcinogenic risk estimation.

S. Epstein and J. Swartz (1988)
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