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Science 26 August 1983:
Vol. 221. no. 4613, pp. 867 - 869
DOI: 10.1126/science.6308764
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Articles

Science, Vol 221, Issue 4613, 867-869
Copyright © 1983 by American Association for the Advancement of Science

articles

Genetic mapping of the mouse proto-oncogene c-sis to chromosome 15

CA Kozak, JF Sears, and MD Hoggan

The mouse homolog (c-sis) of the transforming gene of the simian sarcoma virus was mapped to chromosome 15 by the Southern blot analysis of DNA's from hamster-mouse somatic cell hybrids. Alterations in c-sis expression may thus play a role in the various murine neoplastic diseases characterized by rearrangements or duplications of chromosome 15.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Cellular oncogenes and multistep carcinogenesis.
H Land, L. Parada, and R. Weinberg (1983)
Science 222, 771-778
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