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Science 19 August 1983:
Vol. 221. no. 4612, pp. 754 - 756
DOI: 10.1126/science.6410509

Articles

Science, Vol 221, Issue 4612, 754-756
Copyright © 1983 by American Association for the Advancement of Science


articles

Pancreatic islet allograft prolongation by donor-specific blood transfusions treated with ultraviolet irradiation

H Lau, K Reemtsma, and MA Hardy

Survival of allografts of islets of Langerhans in nonimmunosuppressed adult rats was prolonged by transfusions of donor blood irradiated with ultraviolet light before transplantation across a major histocompatibility barrier. This treatment is donor blood-specific and has produced greater than 160-day survival of transplanted islets without the administration of immunosuppressive agents.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Characterization of immunologic tolerance induced by transfusion of UV-B-irradiated allogeneic mononuclear leukocytes.
K.-J. Kao, E. S. Huang, and S. Donahue (2001)
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Induction of Immunologic Tolerance for Transplantation.
A. A. ROSSINI, D. L. GREINER, and J. P. MORDES (1999)
Physiol Rev 79, 99-141
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Lymphocytes: Window to the Future.
A. N. d. Torre and A. C. Antonacci (1990)
Arch Surg 125, 665-667
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A blood vessel model constructed from collagen and cultured vascular cells.
C. Weinberg and E Bell (1986)
Science 231, 397-400
   Abstract »    PDF »
Prolongation of rat islet allograft survival by direct ultraviolet irradiation of the graft.
H Lau, K Reemtsma, and M. Hardy (1984)
Science 223, 607-609
   Abstract »    PDF »



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