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Science 5 August 1983:
Vol. 221. no. 4610, pp. 553 - 556
DOI: 10.1126/science.6346488
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Articles

Science, Vol 221, Issue 4610, 553-556
Copyright © 1983 by American Association for the Advancement of Science

articles

Expression of the major neurofilament subunit in chicken erythrocytes

BL Granger and E Lazarides

The 70,000-dalton core polypeptide of neurofilaments, thought to exist only in neurons, has been detected in chicken erythrocytes, where it coexists with vimentin and synemin as a component of the intermediate filament network. It is present in the circulating erythroid cells of embryos and young chickens but is nearly absent from the erythroid cells of adults. These findings are inconsistent with current models of intermediate filament expression, but provide another example of unexpected similarities between the nervous and hemopoietic systems.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Continuous growth of vimentin filaments in mouse fibroblasts.
T. R. Coleman and E. Lazarides (1992)
J. Cell Sci. 103, 689-698
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Science. ISSN 0036-8075 (print), 1095-9203 (online)