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Science 29 July 1983:
Vol. 221. no. 4609, pp. 476 - 478
DOI: 10.1126/science.6867724
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Articles

Science, Vol 221, Issue 4609, 476-478
Copyright © 1983 by American Association for the Advancement of Science

articles

Endogenous inhibitors of monoamine oxidase present in human cerebrospinal fluid

RE Becker, C Giambalvo, RA Fox, and M Macho

Inhibitory activity against the enzyme monoamine oxidase is present in low molecular weight fractions (less than 100,000) of human cerebrospinal fluid. These endogenous substances of different molecular weights (3000 to more than 35,000) act like monoamine oxidase inhibitor drugs to inhibit both type A and type B monoamine oxidase.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)