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Science 29 July 1983:
Vol. 221. no. 4609, pp. 468 - 470
DOI: 10.1126/science.6306766
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Articles

Science, Vol 221, Issue 4609, 468-470
Copyright © 1983 by American Association for the Advancement of Science

articles

Minor histone 2A variants and ubiquinated forms in the native H2A:H2B dimer

CL Hatch, WM Bonner, and EN Moudrianakis

Histone octamers from calf thymus were separated into (H3:H4)2 tetramers and H2A:H2B dimers by chromatography through Sephadex G100. The tetramers and dimers were analyzed for variants, ubiquitin adducts, and proteolyzed forms. The minor histone variants H2A.X and H2A.Z were found to be associated with histone H2B as H2A.X:H2B and H2A.Z:H2B dimers, respectively. Ubiquitin adducts of the H2A's and H2B were also present in H2A:H2B dimers.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
ATP-Driven Exchange of Histone H2AZ Variant Catalyzed by SWR1 Chromatin Remodeling Complex.
G. Mizuguchi, X. Shen, J. Landry, W.-H. Wu, S. Sen, and C. Wu (2004)
Science 303, 343-348
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