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Science 1 July 1983:
Vol. 221. no. 4605, pp. 17 - 23
DOI: 10.1126/science.6407110
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Articles

Science, Vol 221, Issue 4605, 17-23
Copyright © 1983 by American Association for the Advancement of Science

articles

Cost-effective priorities for cancer prevention

MC Weinstein

Faced with limited resources, the United States must set priorities for research to identify preventable causes of cancer. A quantitative approach to priority setting, based on principles of decision analysis and cost-effectiveness analysis, can offer guidance in this process. An illustrative application of such a model suggests that the National Institutes of Health-supported clinical trial of dietary beta-carotene offers a greater expected reduction in cancer mortality per research dollar than carcinogen bioassays of high-volume industrial chemicals such as p-dichlorobenzene. National research priorities should reflect the relative cost-effectiveness of such investments.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Can We Better Prioritize Resources for Cost-Utility Research?.
P. J. Neumann, A. B. Rosen, D. Greenberg, N. V. Olchanski, R. Pande, R. H. Chapman, P. W. Stone, S. Ondategui-Parra, J. Nadai, J. E. Siegel, et al. (2005)
Med Decis Making 25, 429-436
   Abstract »    PDF »
Are Clinical Trials a Cost-effective Investment?.
A. S. Detsky (1989)
JAMA 262, 1795-1800
   Abstract »    PDF »
The Women's Health Trial as an Investment.
N. Urban and M. Baker (1989)
Med Decis Making 9, 59-64
   Abstract »    PDF »
Meta-Analysis in Clinical Research.
K. A. L'ABBE, A. S. DETSKY, and K. O'ROURKE (1987)
Ann Intern Med 107, 224-233
   Abstract »    PDF »
Decision Analysis: A Progress Report.
J. P. KASSIRER, A. J. MOSKOWITZ, J. LAU, and S. G. PAUKER (1987)
Ann Intern Med 106, 275-291
   Abstract »    PDF »


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