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Science 17 June 1983:
Vol. 220. no. 4603, pp. 1279 - 1281
DOI: 10.1126/science.6344216
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Articles
Science, Vol 220, Issue 4603, 1279-1281
Copyright © 1983 by American Association for the Advancement of Science
The genus-specific antigen of Chlamydia: resemblance to the lipopolysaccharide of enteric bacteria
M Nurminen,
M Leinonen,
P Saikku,
and
PH Makela
A strong immunological cross-reaction between a major glycolipid antigen of Chlamydia and the innermost (Re) core of the lipopolysaccharide of enteric bacteria was demonstrated with the aid of mutants in which the Re structure is exposed. The chlamydial glycolipid resembled the Re lipopolysaccharide in molecular size, solubility, and endotoxic properties and may thus be functionally equivalent to lipopolysaccharide, an essential and characteristic component of the outer membrane of Gram-negative bacteria.
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