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Science 3 June 1983:
Vol. 220. no. 4601, pp. 1082 - 1083
DOI: 10.1126/science.6844931
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Articles

Science, Vol 220, Issue 4601, 1082-1083
Copyright © 1983 by American Association for the Advancement of Science

articles

Light and agonists alter pineal N-acetyltransferase induction by vasoactive intestinal polypeptide

A Yuwiler

Vasoactive intestinal polypeptide stimulated serotonin N-acetyltransferase activity in rat pineal glands in organ culture by a postsynaptic action that was independent of the beta-receptor. The magnitude of stimulation could be altered by environmental lighting conditions and by prior exposure to the agonist. Such up- and down-regulation, well known for catecholaminergic stimulation of this system, is compatible with a possible control of the pineal by vasoactive intestinal polypeptide as well as by catecholamines.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The psychopharmacology of the human pineal.
S.A. Checkley and S.B.G. Park (1987)
J Psychopharmacol 1, 109-125
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