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Science 3 June 1983:
Vol. 220. no. 4601, pp. 1059 - 1061
DOI: 10.1126/science.6844926

Articles

Science, Vol 220, Issue 4601, 1059-1061
Copyright © 1983 by American Association for the Advancement of Science


articles

Neural crest cells contribute to normal aorticopulmonary septation

ML Kirby, TF Gale, and DE Stewart

By analyzing the hearts of quail-chick chimeras, it was found that neural crest cells at the level of occipital somites 1 to 3 migrate to the region of the aorticopulmonary septum. Bilateral removal of this neural crest population prior to migration causes malformation of the aorticopulmonary septum resulting in common arterial outflow channels or transposition of the great vessels.


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Large-scale reprogramming of cranial neural crest gene expression by retinoic acid exposure.
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Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells.
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Development 129, 4301-4313
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Cell autonomous requirement for PDGFR{alpha} in populations of cranial and cardiac neural crest cells.
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Development 130, 507-518
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The Homeobox Gene Lbx1 Specifies a Subpopulation of Cardiac Neural Crest Necessary for Normal Heart Development.
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Aortic Root Dilatation After Repair of Tetralogy of Fallot: Pathology From the Past?.
C. A. Warnes and J. S. Child (2002)
Circulation 106, 1310-1311
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Embryogenesis of Transposition of the Great Arteries: A Lesson From the Heart.
M. L. Kirby (2002)
Circ. Res. 91, 87-89
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Cardiac Septation: A Late Contribution of the Embryonic Primary Myocardium to Heart Morphogenesis.
W. H. Lamers and A. F.M. Moorman (2002)
Circ. Res. 91, 93-103
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Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant.
S. Muto, A. Aiba, Y. Saito, K. Nakao, K. Nakamura, K. Tomita, T. Kitamura, M. Kurabayashi, R. Nagai, E. Higashihara, et al. (2002)
Hum. Mol. Genet. 11, 1731-1742
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Neural Crest Migration and Mouse Models of Congenital Heart Disease.
A.D. GITLER, C.B. BROWN, L. KOCHILAS, J. LI, and J.A. EPSTEIN (2002)
Cold Spring Harb Symp Quant Biol 67, 57-62
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Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption.
L. Feiner, A. L. Webber, C. B. Brown, M. M. Lu, L. Jia, P. Feinstein, P. Mombaerts, J. A. Epstein, and J. A. Raper (2001)
Development 128, 3061-3070
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PlexinA2 and semaphorin signaling during cardiac neural crest development.
C. B. Brown, L. Feiner, M.-M. Lu, J. Li, X. Ma, A. L. Webber, L. Jia, J. A. Raper, and J. A. Epstein (2001)
Development 128, 3071-3080
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Cell Lineages and Tissue Boundaries in Cardiac Arterial and Venous Poles : Developmental Patterns, Animal Models, and Implications for Congenital Vascular Diseases.
S. Ausoni and S. Sartore (2001)
Arterioscler Thromb Vasc Biol 21, 312-320
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Cardiac neural crest: the holy grail of cardiac abnormalities?.
M. J.B. van den Hoff and A. F.M. Moorman (2000)
Cardiovasc Res 47, 212-216
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Migration of cardiac neural crest cells in Splotch embryos.
J. Epstein, J Li, D Lang, F Chen, C. Brown, F Jin, M. Lu, M Thomas, E Liu, A Wessels, et al. (2000)
Development 127, 1869-1878
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Fate of the mammalian cardiac neural crest.
X Jiang, D. Rowitch, P Soriano, A. McMahon, and H. Sucov (2000)
Development 127, 1607-1616
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Unique vascular morphology of the fourth aortic arches: possible implications for pathogenesis of type-B aortic arch interruption and anomalous right subclavian artery.
M. Bergwerff, M. C. DeRuiter, S. Hall, R. E. Poelmann, and A. C. Gittenberger-de Groot (1999)
Cardiovasc Res 44, 185-196
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A woman with amenorrhoea.
A Ogunko, K Oboubie, J S Davies, and A Rees (1999)
Postgrad. Med. J. 75, 303-305
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Mechanisms Underlying Aortic Dilatation in Congenital Aortic Valve Malformation.
D. Bonderman, E. Gharehbaghi-Schnell, G. Wollenek, G. Maurer, H. Baumgartner, and I. M. Lang (1999)
Circulation 99, 2138-2143
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A Molecular Pathway Revealing a Genetic Basis for Human Cardiac and Craniofacial Defects.
H. Yamagishi, V. Garg, R. Matsuoka, T. Thomas, and D. Srivastava (1999)
Science 283, 1158-1161
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HIRA, a DiGeorge Syndrome Candidate Gene, Is Required for Cardiac Outflow Tract Septation.
M. J. Farrell, H. Stadt, K. T. Wallis, P. Scambler, R. L. Hixon, R. Wolfe, L. Leatherbury, and M. L. Kirby (1999)
Circ. Res. 84, 127-135
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Transgenic rescue of congenital heart disease and spina bifida in Splotch mice.
J Li, K. Liu, F Jin, M. Lu, and J. Epstein (1999)
Development 126, 2495-2503
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Anomalous right pulmonary artery origins in association with the fetal valproate syndrome.
C N Mo and E J Ladusans (1999)
J. Med. Genet. 36, 83-84
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Recent advances in cardiovascular development: promise for the future.
H.S. Baldwin and M. Artman (1998)
Cardiovasc Res 40, 456-468
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Sox4-Deficiency Syndrome in Mice Is an Animal Model for Common Trunk.
J. Ya, M. W. Schilham, P. A. J. de Boer, A. F. M. Moorman, H. Clevers, and W. H. Lamers (1998)
Circ. Res. 83, 986-994
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Normal Development of the Outflow Tract in the Rat.
J. Ya, M. J. B. van den Hoff, P. A. J. de Boer, S. Tesink-Taekema, D. Franco, A. F. M. Moorman, and W. H. Lamers (1998)
Circ. Res. 82, 464-472
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Neural Crest Cell Contribution to the Developing Circulatory System : Implications for Vascular Morphology?.
M. Bergwerff, M. E. Verberne, M. C. DeRuiter, R. E. Poelmann, and A. C. Gittenberger-de-Groot (1998)
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Relation of genotype 22q11 deletion to phenotype of pulmonary vessels in tetralogy of Fallot and pulmonary atresia-ventricular septal defect.
M Chessa, G Butera, P Bonhoeffer, L Iserin, J Kachaner, S Lyonnet, A Munnich, D Sidi, and D Bonnet (1998)
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Development 125, 4359-4367
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Developmental remodeling and shortening of the cardiac outflow tract involves myocyte programmed cell death.
M Watanabe, A Choudhry, M Berlan, A Singal, E Siwik, S Mohr, and S. Fisher (1998)
Development 125, 3809-3820
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Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene.
H Yanagisawa, M Yanagisawa, R. Kapur, J. Richardson, S. Williams, D. Clouthier, D de Wit, N Emoto, and R. Hammer (1998)
Development 125, 825-836
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Familial Axenfeld-Rieger Anomaly, Atrial Septal Defect, and Sensorineural Hearing Loss: A Possible New Genetic Syndrome.
E. T. Cunningham Jr, D. Eliott, N. R. Miller, I. H. Maumenee, and W. R. Green (1998)
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Production of a Monoclonal Antibody by In Vitro Immunization That Recognizes a Native Chondroitin Sulfate Epitope in the Embryonic Chick Limb and Heart.
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J. Histochem. Cytochem. 45, 1567-1582
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Development of a lethal congenital heart defect in the splotch (Pax3) mutant mouse.
S. J Conway, D. J Henderson, M. L Kirby, R. H Anderson, and A. J Copp (1997)
Cardiovasc Res 36, 163-173
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Endothelin-1 Alters the Contractile Phenotype of Cultured Embryonic Smooth Muscle Cells.
S. A. Fisher, M. Ikebe, and F. Brozovich (1997)
Circ. Res. 80, 885-893
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Chromosome 22q1l Deletion Syndrome: An Update and Review for the Primary Pediatrician.
J. A. Thomas and J. M. Graham Jr. (1997)
Clinical Pediatrics 36, 253-266
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Genetic Disorders of Cardiac Morphogenesis : The DiGeorge and Velocardiofacial Syndromes.
E. Goldmuntz and B. S. Emanuel (1997)
Circ. Res. 80, 437-443
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Unilateral Vitelline Vein Ligation Alters Intracardiac Blood Flow Patterns and Morphogenesis in the Chick Embryo.
B. Hogers, M.C. DeRuiter, A.C. Gittenberger-de Groot, and R.E. Poelmann (1997)
Circ. Res. 80, 473-481
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Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch (Sp2H) mutant.
S. Conway, D. Henderson, and A. Copp (1997)
Development 124, 505-514
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Glial cell line-derived neurotrophic factor promotes the development of adrenergic neurons in mouse neural crest cultures.
G. D. Maxwell, K. Reid, A. Elefanty, P. F. Bartlett, and M. Murphy (1996)
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SM22{alpha}, a Marker of Adult Smooth Muscle, Is Expressed in Multiple Myogenic Lineages During Embryogenesis.
L. Li, J. M. Miano, P. Cserjesi, and E. N. Olson (1996)
Circ. Res. 78, 188-195
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Developmental Pattern of Expression and Genomic Organization of the Calponin-h1 Gene.
F. F. Samaha, H. S. Ip, E. E. Morrisey, J. Seltzer, Z. Tang, J. Solway, and M. S. Parmacek (1996)
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Noonan Syndrome and Neuroblastoma.
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Prenatal Craniofacial Development: New Insights On Normal and Abnormal Mechanisms.
M.C. Johnston and P.T. Bronsky (1995)
Critical Reviews in Oral Biology & Medicine 6, 25-79
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Prenatal Craniofacial Development: New Insights on Normal and Abnormal Mechanisms.
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Critical Reviews in Oral Biology & Medicine 6, 368-422
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RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis..
H M Sucov, E Dyson, C L Gumeringer, J Price, K R Chien, and R M Evans (1994)
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Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues..
C I Brannan, A S Perkins, K S Vogel, N Ratner, M L Nordlund, S W Reid, A M Buchberg, N A Jenkins, L F Parada, and N G Copeland (1994)
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Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants.
C Mendelsohn, D Lohnes, D Decimo, T Lufkin, M LeMeur, P Chambon, and M Mark (1994)
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Regulative capacity of the cranial neural tube to form neural crest.
T Scherson, G Serbedzija, S Fraser, and M Bronner-Fraser (1993)
Development 118, 1049-1062
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The triple origin of skull in higher vertebrates: a study in quail-chick chimeras.
G. Couly, P. Coltey, and N. Le Douarin (1993)
Development 117, 409-429
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The Pattern of Cardiovascular Malformation in the CHARGE Association.
A. E. Lin, A. J. Chin, W. Devine, S. C. Park, and E. Zackai (1987)
Arch Pediatr Adolesc Med 141, 1010-1013
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Cardiac Embryology: Its Relevance to Congenital Heart Disease.
E. B. Clark (1986)
Arch Pediatr Adolesc Med 140, 41-44
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Dependence of thymus development on derivatives of the neural crest.
D. Bockman and M. Kirby (1984)
Science 223, 498-500
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Regulation of apoptosis in the endocardial cushions of the developing chick heart.
W. M. Keyes and E. J. Sanders (2002)
Am J Physiol Cell Physiol 282, C1348-C1360
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Cardiovascular Defects Associated With Abnormalities in Midline Development in the Loop-tail Mouse Mutant.
D. J. Henderson, S. J. Conway, N. D. E. Greene, D. Gerrelli, J. N. Murdoch, R. H. Anderson, and A. J. Copp (2001)
Circ. Res. 89, 6-12
   Abstract »    Full Text »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)