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Science 3 June 1983:
Vol. 220. no. 4601, pp. 1057 - 1059
DOI: 10.1126/science.6342138
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Articles

Science, Vol 220, Issue 4601, 1057-1059
Copyright © 1983 by American Association for the Advancement of Science

articles

Glucose stimulation of the antilipolytic effect of insulin in humans

P Arner, J Bolinder, and J Ostman

Dose-response studies of the inhibition of lipolysis by insulin in isolated human adipocytes were conducted with the use of a sensitive bioluminescent assay of glycerol release. The addition of glucose to the incubation medium was associated with an increase in insulin sensitivity and an increase in the maximum insulin effect. The results suggest that glucose plays an important role in regulating the antilipolytic action of insulin in humans.


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Prevention of Fatty Liver in Transition Dairy Cows by Subcutaneous Injections of Glucagon.
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J Dairy Sci 89, 1533-1545
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Combined Hyperinsulinemia and Hyperglycemia, But Not Hyperinsulinemia Alone, Suppress Human Skeletal Muscle Lipolytic Activity in Vivo.
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J. Clin. Endocrinol. Metab. 89, 4693-4700
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