Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Science Policy Alerts

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 27 May 1983:
Vol. 220. no. 4600, pp. 965 - 967
DOI: 10.1126/science.6844922
Prev | Table of Contents | Next

Articles

Science, Vol 220, Issue 4600, 965-967
Copyright © 1983 by American Association for the Advancement of Science

articles

Cytotoxicity of a perfluorocarbon blood substitute to macrophages in vitro

R Bucala, M Kawakami, and A Cerami

Murine macrophage and macrophage-depleted splenocyte cultures were incubated under ambient oxygen with a commercially available perfluorocarbon blood substitute. The perfluorocarbon preparation was found to be selectively cytotoxic to macrophages. This finding may be significant in view of the preliminary therapeutic usage of these preparations. In addition, perfluorocarbons may be useful as a means of selectively removing macrophages from tissue and organ cultures.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Effects of a perfluorochemical emulsion on the fate of circulating Pseudomonas aeruginosa.
J. D. Brain, R. M. Molina, M. M. DeCamp, and A. E. Warner (1999)
Am J Physiol Lung Cell Mol Physiol 276, L1037-L1045
   Abstract »    Full Text »    PDF »


ADVERTISEMENT
Click Me!

ADVERTISEMENT
Click Me!

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)