Science 29 April 1983: Vol. 220. no. 4596, pp. 472 - 477 DOI: 10.1126/science.6836290

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Articles

Oxidative Stress in Prehypertension: Rationale for Antioxidant Clinical Trials.

S. Nambiar, S. Viswanathan, B. Zachariah, N. Hanumanthappa, and Sridhar Gopalakrishna Magadi (2009)
Angiology 60, 221-234
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RNAi-Mediated Silencing of Nuclear Factor Erythroid-2-Related Factor 2 Gene Expression in Non-Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy.

A. Singh, S. Boldin-Adamsky, R. K. Thimmulappa, S. K. Rath, H. Ashush, J. Coulter, A. Blackford, S. N. Goodman, F. Bunz, W. H. Watson, et al. (2008)
Cancer Res. 68, 7975-7984
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The interactions between cysteamine, cystine and cumulus cells increase the intracellular glutathione level and developmental capacity of goat cumulus-denuded oocytes.

P. Zhou, Y.-G. Wu, Q. Li, G.-C. Lan, G. Wang, D. Gao, and J.-H. Tan (2008)
Reproduction 135, 605-611
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The Treatment of Pulmonary Diseases and Respiratory-Related Conditions with Inhaled (Nebulized or Aerosolized) Glutathione.

J. Prousky (2008)
Evid. Based Complement. Altern. Med. 5, 27-35
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Effect of Amentoflavone on the Inhibition of Pulmonary Metastasis Induced by B16F-10 Melanoma Cells in C57BL/6 Mice.

C. Guruvayoorappan and G. Kuttan (2007)
Integr Cancer Ther 6, 185-197
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CHARACTERIZATION OF NATURAL ANTIMONY RESISTANCE IN LEISHMANIA DONOVANI ISOLATES.

M. K. MITTAL, S. RAI, ASHUTOSH, RAVINDER, S. GUPTA, S. SUNDAR, and N. GOYAL (2007)
Am J Trop Med Hyg 76, 681-688
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Bcl-2 and Mn-SOD Antisense Oligodeoxynucleotides and a Glutamine-enriched Diet Facilitate Elimination of Highly Resistant B16 Melanoma Cells by Tumor Necrosis Factor-{alpha} and Chemotherapy.

M. Benlloch, S. Mena, P. Ferrer, E. Obrador, M. Asensi, J. A. Pellicer, J. Carretero, A. Ortega, and J. M. Estrela (2006)
J. Biol. Chem. 281, 69-79
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Interaction of radiation- and bleomycin-induced lesions and influence of glutathione level on the interaction.

A. Dutta, A. Chakraborty, A. Saha, S. Ray, and A. Chatterjee (2005)
Mutagenesis 20, 329-335
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Valproic Acid II: Effects on Oxidative Stress, Mitochondrial Membrane Potential, and Cytotoxicity in Glutathione-Depleted Rat Hepatocytes.

V. Tong, X. W. Teng, T. K. H. Chang, and F. S. Abbott (2005)
Toxicol. Sci. 86, 436-443
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Acceleration of Glutathione Efflux and Inhibition of {gamma}-Glutamyltranspeptidase Sensitize Metastatic B16 Melanoma Cells to Endothelium-induced Cytotoxicity.

M. Benlloch, A. Ortega, P. Ferrer, R. Segarra, E. Obrador, M. Asensi, J. Carretero, and J. M. Estrela (2005)
J. Biol. Chem. 280, 6950-6959
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BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species-dependent DNA double-strand breaks.

M. O. Nowicki, R. Falinski, M. Koptyra, A. Slupianek, T. Stoklosa, E. Gloc, M. Nieborowska-Skorska, J. Blasiak, and T. Skorski (2004)
Blood 104, 3746-3753
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Protection of Porcine Oocytes Against Cell Damage Caused by Oxidative Stress During In Vitro Maturation: Role of Superoxide Dismutase Activity in Porcine Follicular Fluid.

H. Tatemoto, N. Muto, I. Sunagawa, A. Shinjo, and T. Nakada (2004)
Biol Reprod 71, 1150-1157
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Imexon-Induced Apoptosis in Multiple Myeloma Tumor Cells Is Caspase-8 Dependent.

A. M. Evens, S. Prachand, B. Shi, M. Paniaqua, L. I. Gordon, and R. B. Gartenhaus (2004)
Clin. Cancer Res. 10, 1481-1491
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Evidence for a Role of p38 Kinase in Hypoxia-inducible Factor 1-independent Induction of Vascular Endothelial Growth Factor Expression by Sodium Arsenite.

M. C. A. Duyndam, S. T. M. Hulscher, E. van der Wall, H. M. Pinedo, and E. Boven (2003)
J. Biol. Chem. 278, 6885-6895
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Cell death and its suppression in human ovarian tissue culture.

M. Otala, K. Erkkila, T. Tuuri, J. Sjoberg, L. Suomalainen, A-M. Suikkari, V. Pentikainen, and L. Dunkel (2002)
Mol. Hum. Reprod. 8, 228-236
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Antidiabetic Effect of a Prodrug of Cysteine, L-2-Oxothiazolidine-4-carboxylic Acid, through CD38 Dimerization and Internalization.

M.-K. Han, S.-J. Kim, Y.-R. Park, Y.-M. Shin, H.-J. Park, K.-J. Park, K.-H. Park, H.-K. Kim, S.-I. Jang, N.-H. An, et al. (2002)
J. Biol. Chem. 277, 5315-5321
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Induction of Vascular Endothelial Growth Factor Expression and Hypoxia-inducible Factor 1alpha Protein by the Oxidative Stressor Arsenite.

M. C. A. Duyndam, T. M. Hulscher, D. Fontijn, H. M. Pinedo, and E. Boven (2001)
J. Biol. Chem. 276, 48066-48076
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Enhancement of Developmental Competence after In Vitro Fertilization of Porcine Oocytes by Treatment with Ascorbic Acid 2-O-{alpha}-Glucoside During In Vitro Maturation.

H. Tatemoto, K. Ootaki, K. Shigeta, and N. Muto (2001)
Biol Reprod 65, 1800-1806
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Long-Term Smoking Causes Nitroglycerin Resistance in Platelets by Depletion of Intraplatelet Glutathione.

N. Haramaki, H. Ikeda, Y. Takajo, A. Katoh, S. Kanaya, S. Shintani, R. Haramaki, T. Murohara, and T. Imaizumi (2001)
Arterioscler Thromb Vasc Biol 21, 1852-1856
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Chronic ethanol consumption exacerbates microcirculatory damage in rat mesentery after reperfusion.

J.-Y. Han, S. Miura, Y. Akiba, H. Higuchi, S. Kato, H. Suzuki, H. Yokoyama, and H. Ishii (2001)
Am J Physiol Gastrointest Liver Physiol 280, G939-G948
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Protective effects of n-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat.

S. CUZZOCREA, E. MAZZON, L. DUGO, I. SERRAINO, A. CICCOLO, T. CENTORRINO, A. DE SARRO, and A. P. CAPUTI (2001)
FASEB J 15, 1187-1200
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Effects of Sodium Pyruvate in Nonserum Maturation Medium on Maturation, Fertilization, and Subsequent Development of Bovine Oocytes With or Without Cumulus Cells.

M. Geshi, N. Takenouchi, N. Yamauchi, and T. Nagai (2000)
Biol Reprod 63, 1730-1734
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Protection of Porcine Oocytes Against Apoptotic Cell Death Caused by Oxidative Stress During In Vitro Maturation: Role of Cumulus Cells.

H. Tatemoto, N. Sakurai, and N. Muto (2000)
Biol Reprod 63, 805-810
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Thiol homeostasis and supplements in physical exercise.

C. K Sen and L. Packer (2000)
Am. J. Clinical Nutrition 72, 653S-669
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p38 MAP kinase pathway regulates angiotensin II-induced contraction of rat vascular smooth muscle.

S. Meloche, J. Landry, J. Huot, F. Houle, F. Marceau, and E. Giasson (2000)
Am J Physiol Heart Circ Physiol 279, H741-H751
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Induction of Oxidative Stress by Glutathione Depletion Causes Severe Hypertension in Normal Rats.

N. D. Vaziri, X. Q. Wang, F. Oveisi, and B. Rad (2000)
Hypertension 36, 142-146
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Escherichia coli Resistance to Chlorine and Glutathione Synthesis in Response to Oxygenation and Starvation.

S. Saby, P. Leroy, and J.-C. Block (1999)
Appl. Envir. Microbiol. 65, 5600-5603
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Supplementation of N-acetylcysteine inhibits NF{kappa}B activation and protects against alloxan-induced diabetes in CD-1 mice.

E. HO, G. CHEN, and T. M. BRAY (1999)
FASEB J 13, 1845-1854
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Glutathione reverses endothelial dysfunction and improves nitric oxide bioavailability.

A. Prasad, N. P. Andrews, F. A. Padder, M. Husain, and A. A. Quyyumi (1999)
J. Am. Coll. Cardiol. 34, 507-514
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Is NF-{kappa}B the sensor of oxidative stress?.

N. LI and M. KARIN (1999)
FASEB J 13, 1137-1143
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Activation of Stress Signaling Pathways by the End Product of Lipid Peroxidation. 4-HYDROXY-2-NONENAL IS A POTENTIAL INDUCER OF INTRACELLULAR PEROXIDE PRODUCTION.

K. Uchida, M. Shiraishi, Y. Naito, Y. Torii, Y. Nakamura, and T. Osawa (1999)
J. Biol. Chem. 274, 2234-2242
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Reduced glutathione inhibits {beta}-NAD+-activated non-selective cation currents in the CRI-G1 rat insulin-secreting cell line.

P. S Herson and M. L J Ashford (1999)
J. Physiol. 514, 47-57
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L-2-Oxothiazolidine-4-Carboxylic Acid Prevents Endotoxin-induced Cardiac Dysfunction.

B. Y. POON, C. M. GODDARD, C. D. LEAF, J. A. RUSSELL, and K. R. WALLEY (1998)
Am. J. Respir. Crit. Care Med. 158, 1109-1113
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Transcriptionally Active Nuclear Factor-{kappa}B by Tumor Necrosis Factor-{alpha} and Its Inhibition by Antioxidants in Rat Thyroid FRTL-5 Cells.

T. Kikumori, F. Kambe, T. Nagaya, T. Imai, H. Funahashi, and H. Seo (1998)
Endocrinology 139, 1715-1722
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Impairment of intestinal glutathione synthesis in patients with inflammatory bowel disease.

B Sido, V Hack, A Hochlehnert, H Lipps, C Herfarth, and W Droge (1998)
Gut 42, 485-492
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Fully automated assay for total homocysteine, cysteine, cysteinylglycine, glutathione, cysteamine, and 2-mercaptopropionylglycine in plasma and urine.

A. Pastore, R. Massoud, C. Motti, A. L. Russo, G. Fucci, C. Cortese, and G. Federici (1998)
Clin. Chem. 44, 825-832
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Metabolism of Cysteine Is Modified During the Acute Phase of Sepsis in Rats.

T. Malmezat, D. Breuillé, C. Pouyet, P. P. Mirand, and C. Obled (1998)
J. Nutr. 128, 97-105
 |  Abstract »  |  Full Text »

Inhibition of the Neutral Magnesium-dependent Sphingomyelinase by Glutathione.

B. Liu and Y. A. Hannun (1997)
J. Biol. Chem. 272, 16281-16287
 |  Abstract »  |  Full Text »  |  PDF »

Cytosolic Phospholipase A2 (PLA2), but Not Secretory PLA2, Potentiates Hydrogen Peroxide Cytotoxicity in Kidney Epithelial Cells.

A. Sapirstein, R. A. Spech, R. Witzgall, and J. V. Bonventre (1996)
J. Biol. Chem. 271, 21505-21513
 |  Abstract »  |  Full Text »  |  PDF »

Peroxynitrite-induced Accumulation of Cyclic GMP in Endothelial Cells and Stimulation of Purified Soluble Guanylyl Cyclase.

B. Mayer, A. Schrammel, P. Klatt, D. Koesling, and K. Schmidt (1995)
J. Biol. Chem. 270, 17355-17360
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Randomized, Double-Blind, Controlled Trial of Acetylcysteine in Amyotrophic Lateral Sclerosis.

E. S. Louwerse, G. J. Weverling, P. M. M. Bossuyt, F. E. P. Meyjes, and J. M. B. V. de Jong (1995)
Arch Neurol 52, 559-564
 |  Abstract »  |  PDF »

Near-total glutathione depletion and age-specific cataracts induced by buthionine sulfoximine in mice.

H. Calvin, C Medvedovsky, and B. Worgul (1986)
Science 233, 553-555
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Detoxification of Genotoxic Compounds as a Threshold Mechanism Limiting Their Carcinogenicity.

S. De Flora (1984)
Toxicol Pathol 12, 337-343
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Glutathione and Caffeine Antagonize the Sperm-Immobilizing Effect of a Vaginal Contraceptive.

C.Y. Hong, B.N. Chiang, J. Ku, and Y.H. Wei (1984)
Human and Experimental Toxicology 3, 271-277
 |  Abstract »  |  PDF »

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