Science 11 March 1983: Vol. 219. no. 4589, pp. 1184 - 1190 DOI: 10.1126/science.6338589

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Articles

Synaptic Activity-Mediated Suppression of p53 and Induction of Nuclear Calcium-Regulated Neuroprotective Genes Promote Survival through Inhibition of Mitochondrial Permeability Transition.

D. Lau and H. Bading (2009)
J. Neurosci. 29, 4420-4429
 |  Abstract »  |  Full Text »  |  PDF »

Gonadal Steroids Maintain 24 h Acetylcholine Release in the Hippocampus: Organizational and Activational Effects in Behaving Rats.

D. Mitsushima, K. Takase, T. Funabashi, and F. Kimura (2009)
J. Neurosci. 29, 3808-3815
 |  Abstract »  |  Full Text »  |  PDF »

Functional Convergence of Dopaminergic and Cholinergic Input Is Critical for Hippocampus-Dependent Working Memory.

L. A. B. Wisman, G. Sahin, M. Maingay, G. Leanza, and D. Kirik (2008)
J. Neurosci. 28, 7797-7807
 |  Abstract »  |  Full Text »  |  PDF »

Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology.

A. Berson, M. Knobloch, M. Hanan, S. Diamant, M. Sharoni, D. Schuppli, B. C. Geyer, R. Ravid, T. S. Mor, R. M. Nitsch, et al. (2008)
Brain 131, 109-119
 |  Abstract »  |  Full Text »  |  PDF »

Nitric Oxide Activates Leak K+ Currents in the Presumed Cholinergic Neuron of Basal Forebrain.

Y. Kang, Y. Dempo, A. Ohashi, M. Saito, H. Toyoda, H. Sato, H. Koshino, Y. Maeda, and T. Hirai (2007)
J Neurophysiol 98, 3397-3410
 |  Abstract »  |  Full Text »  |  PDF »

SPECT imaging in dementia.

S L PIMLOTT and K P EBMEIER (2007)
Br. J. Radiol. 80, S153-S159
 |  Abstract »  |  Full Text »  |  PDF »

Effects of estrogen against LPS-induced inflammation and toxicity in primary rat glial and neuronal cultures.

M. Tenenbaum, A. N. Azab, and J. Kaplanski (2007)
Innate Immunity 13, 158-166
 |  Abstract »  |  PDF »

Wnt-7a Induces Presynaptic Colocalization of {alpha}7-Nicotinic Acetylcholine Receptors and Adenomatous Polyposis Coli in Hippocampal Neurons.

G. G. Farias, A. S. Valles, M. Colombres, J. A. Godoy, E. M. Toledo, R. J. Lukas, F. J. Barrantes, and N. C. Inestrosa (2007)
J. Neurosci. 27, 5313-5325
 |  Abstract »  |  Full Text »  |  PDF »

References.

(2007)
PsychiatryOnline CME 2007, 2
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D1-like dopamine receptors selectively block P/Q-type calcium channels to reduce glutamate release onto cholinergic basal forebrain neurones of immature rats.

T. Momiyama and Y. Fukazawa (2007)
J. Physiol. 580, 103-117
 |  Abstract »  |  Full Text »  |  PDF »

Noncholinergic Lesions of the Medial Septum Impair Sequential Learning of Different Spatial Locations.

T. A. Dwyer, R. J. Servatius, and K. C. H. Pang (2007)
J. Neurosci. 27, 299-303
 |  Abstract »  |  Full Text »  |  PDF »

Dissecting the signaling pathway of nicotine-mediated neuroprotection in a mouse Alzheimer disease model.

Q. Liu, J. Zhang, H. Zhu, C. Qin, Q. Chen, and B. Zhao (2007)
FASEB J 21, 61-73
 |  Abstract »  |  Full Text »  |  PDF »

Alzheimer's disease and anaesthesia: implications for the central cholinergic system.

V. Fodale, D. Quattrone, C. Trecroci, V. Caminiti, and L. B. Santamaria (2006)
Br. J. Anaesth. 97, 445-452
 |  Abstract »  |  Full Text »  |  PDF »

CAAT/Enhancer-binding Protein {delta} and cAMP-response Element-binding Protein Mediate Inducible Expression of the Nerve Growth Factor Gene in the Central Nervous System.

C. S. McCauslin, V. Heath, A. M. Colangelo, R. Malik, S. Lee, A. Mallei, I. Mocchetti, and P. F. Johnson (2006)
J. Biol. Chem. 281, 17681-17688
 |  Abstract »  |  Full Text »  |  PDF »

Functional pharmacology in human brain..

M. Raiteri (2006)
Pharmacol. Rev. 58, 162-193
 |  Abstract »  |  Full Text »  |  PDF »

Estrogen Induces Estrogen Receptor {alpha}-Dependent cAMP Response Element-Binding Protein Phosphorylation via Mitogen Activated Protein Kinase Pathway in Basal Forebrain Cholinergic Neurons In Vivo.

E. M. Szego, K. Barabas, J. Balog, N. Szilagyi, K. S. Korach, G. Juhasz, and I. M. Abraham (2006)
J. Neurosci. 26, 4104-4110
 |  Abstract »  |  Full Text »  |  PDF »

In vivo cholinergic circuit evaluation in frontotemporal and Alzheimer dementias.

V. Di Lazzaro, F. Pilato, M. Dileone, E. Saturno, A. Oliviero, C. Marra, A. Daniele, F. Ranieri, G. Gainotti, and P. A. Tonali (2006)
Neurology 66, 1111-1113
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Subchronic Treatment of Memantine, Galantamine, and Nicotine in the Brain of Tg2576 (APPswe) Transgenic Mice.

C. Unger, M. M. Svedberg, W.-F. Yu, M. M. Hedberg, and A. Nordberg (2006)
J. Pharmacol. Exp. Ther. 317, 30-36
 |  Abstract »  |  Full Text »  |  PDF »

Cholinergically mediated augmentation of cerebral perfusion in Alzheimer's disease and related cognitive disorders: the cholinergic-vascular hypothesis..

J. A. H. R. Claassen and R. W. M. M. Jansen (2006)
J. Gerontol. A Biol. Sci. Med. Sci. 61, 267-271
 |  Abstract »  |  Full Text »  |  PDF »

Simultaneous Release of Glutamate and Acetylcholine from Single Magnocellular "Cholinergic" Basal Forebrain Neurons.

T. G.J. Allen, F. C. Abogadie, and D. A. Brown (2006)
J. Neurosci. 26, 1588-1595
 |  Abstract »  |  Full Text »  |  PDF »

Orexin (Hypocretin) Effects on Constitutively Active Inward Rectifier K+ Channels in Cultured Nucleus Basalis Neurons.

Q. V. Hoang, P. Zhao, S. Nakajima, and Y. Nakajima (2004)
J Neurophysiol 92, 3183-3191
 |  Abstract »  |  Full Text »  |  PDF »

M2 Muscarinic Acetylcholine Receptor Knock-Out Mice Show Deficits in Behavioral Flexibility, Working Memory, and Hippocampal Plasticity.

T. Seeger, I. Fedorova, F. Zheng, T. Miyakawa, E. Koustova, J. Gomeza, A. S. Basile, C. Alzheimer, and J. Wess (2004)
J. Neurosci. 24, 10117-10127
 |  Abstract »  |  Full Text »  |  PDF »

Cholinergic Drugs for Alzheimer's Disease Enhance in Vitro Dopamine Release.

L. Zhang, F.-M. Zhou, and J. A. Dani (2004)
Mol. Pharmacol. 66, 538-544
 |  Abstract »  |  Full Text »  |  PDF »

Cortical Cholinergic Function and Deficits in Visual Attentional Performance in Rats Following 192 IgG-Saporin-induced Lesions of the Medial Prefrontal Cortex.

J. W. Dalley, D. E. Theobald, P. Bouger, Y. Chudasama, R. N. Cardinal, and T. W. Robbins (2004)
Cereb Cortex 14, 922-932
 |  Abstract »  |  Full Text »  |  PDF »

Par-4 Inhibits Choline Uptake by Interacting with CHT1 and Reducing Its Incorporation on the Plasma Membrane.

J. Xie and Q. Guo (2004)
J. Biol. Chem. 279, 28266-28275
 |  Abstract »  |  Full Text »  |  PDF »

From The Cover: Low acetylcholine during slow-wave sleep is critical for declarative memory consolidation.

S. Gais and J. Born (2004)
PNAS 101, 2140-2144
 |  Abstract »  |  Full Text »  |  PDF »

Acetylcholine, Histamine, and Cognition: Two Sides of the Same Coin.

P. Blandina, M. Efoudebe, G. Cenni, P. Mannaioni, and M. B. Passani (2004)
Learn. Mem. 11, 1-8
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Acetylcholine and Olfactory Perceptual Learning.

D. A. Wilson, M. L. Fletcher, and R. M. Sullivan (2004)
Learn. Mem. 11, 28-34
 |  Abstract »  |  Full Text »  |  PDF »

The Cholinergic Lesion of Alzheimer's Disease: Pivotal Factor or Side Show?.

M. Mesulam (2004)
Learn. Mem. 11, 43-49
 |  Abstract »  |  Full Text »  |  PDF »

Galantamine Facilitates Acquisition of Hippocampus-Dependent Trace Eyeblink Conditioning in Aged Rabbits.

A. P. Weible, M. M. Oh, G. Lee, and J. F. Disterhoft (2004)
Learn. Mem. 11, 108-115
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Galantamine Facilitates Acquisition of a Trace-Conditioned Eyeblink Response in Healthy, Young Rabbits.

B. B. Simon, B. Knuckley, and D. A. Powell (2004)
Learn. Mem. 11, 116-122
 |  Abstract »  |  Full Text »  |  PDF »

A randomised placebo controlled study to assess the effects of cholinergic treatment on muscarinic receptors in Alzheimer's disease.

P M Kemp, C Holmes, S Hoffmann, S Wilkinson, M Zivanovic, J Thom, L Bolt, J Fleming, and D G Wilkinson (2003)
J. Neurol. Neurosurg. Psychiatry 74, 1567-1570
 |  Abstract »  |  Full Text »  |  PDF »

Effect of {beta}-Amyloid Peptide 1-42 on the Cytoprotective Action Mediated by {alpha}7 Nicotinic Acetylcholine Receptors in Growth Factor-Deprived Differentiated PC-12 Cells.

X. D. Li and J. J. Buccafusco (2003)
J. Pharmacol. Exp. Ther. 307, 670-675
 |  Abstract »  |  Full Text »  |  PDF »

Regulated Intramembrane Proteolysis of the p75 Neurotrophin Receptor Modulates Its Association with the TrkA Receptor.

K.-M. Jung, S. Tan, N. Landman, K. Petrova, S. Murray, R. Lewis, P. K. Kim, D. S. Kim, S. H. Ryu, M. V. Chao, et al. (2003)
J. Biol. Chem. 278, 42161-42169
 |  Abstract »  |  Full Text »  |  PDF »

Impaired Modulation of GABAergic Transmission by Muscarinic Receptors in a Mouse Transgenic Model of Alzheimer's Disease.

P. Zhong, Z. Gu, X. Wang, H. Jiang, J. Feng, and Z. Yan (2003)
J. Biol. Chem. 278, 26888-26896
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Muscarinic Receptors Inhibits beta -Amyloid Peptide-induced Signaling in Cortical Slices.

Z. Gu, P. Zhong, and Z. Yan (2003)
J. Biol. Chem. 278, 17546-17556
 |  Abstract »  |  Full Text »  |  PDF »

Muscarinic Potentiation of GABAA Receptor Currents Is Gated by Insulin Signaling in the Prefrontal Cortex.

X.-H. Ma, P. Zhong, Z. Gu, J. Feng, and Z. Yan (2003)
J. Neurosci. 23, 1159-1168
 |  Abstract »  |  Full Text »  |  PDF »

Two different inward rectifier K+ channels are effectors for transmitter-induced slow excitation in brain neurons.

D. Bajic, M. Koike, A. M. Albsoul-Younes, S. Nakajima, and Y. Nakajima (2002)
PNAS 99, 14494-14499
 |  Abstract »  |  Full Text »  |  PDF »

Amyloid Precursor Protein, Presenilins, and alpha -Synuclein: Molecular Pathogenesis and Pharmacological Applications in Alzheimer's Disease.

Y.-H. Suh and F. Checler (2002)
Pharmacol. Rev. 54, 469-525
 |  Abstract »  |  Full Text »  |  PDF »

Noninvasive in vivo assessment of cholinergic cortical circuits in AD using transcranial magnetic stimulation.

V. Di Lazzaro, A. Oliviero, P. A. Tonali, C. Marra, A. Daniele, P. Profice, E. Saturno, F. Pilato, C. Masullo, and J. C. Rothwell (2002)
Neurology 59, 392-397
 |  Abstract »  |  Full Text »  |  PDF »

The Nicotinic Allosteric Potentiating Ligand Galantamine Facilitates Synaptic Transmission in the Mammalian Central Nervous System.

M. D. Santos, M. Alkondon, E. F. R. Pereira, Y. Aracava, H. M. Eisenberg, A. Maelicke, and E. X. Albuquerque (2002)
Mol. Pharmacol. 61, 1222-1234
 |  Abstract »  |  Full Text »  |  PDF »

Cholinergic Changes in the APP23 Transgenic Mouse Model of Cerebral Amyloidosis.

S. Boncristiano, M. E. Calhoun, P. H. Kelly, M. Pfeifer, L. Bondolfi, M. Stalder, A. L. Phinney, D. Abramowski, C. Sturchler-Pierrat, A. Enz, et al. (2002)
J. Neurosci. 22, 3234-3243
 |  Abstract »  |  Full Text »  |  PDF »

Attenuation of Scopolamine-Induced and Age-Associated Memory Impairments by the Sigma and 5-Hydroxytryptamine1A Receptor Agonist OPC-14523 (1-{3-[4-(3-chlorophenyl)-1-piperazinyl]propyl}-5-methoxy-3,4-dihydro-2[1H]-quinolinone monomethanesulfonate).

K. Tottori, M. Nakai, Y. Uwahodo, T. Miwa, S. Yamada, Y. Oshiro, T. Kikuchi, and C. A. Altar (2002)
J. Pharmacol. Exp. Ther. 301, 249-257
 |  Abstract »  |  Full Text »  |  PDF »

Complete Deletion of the Neurotrophin Receptor p75NTR Leads to Long-Lasting Increases in the Number of Basal Forebrain Cholinergic Neurons.

T. Naumann, E. Casademunt, E. Hollerbach, J. Hofmann, G. Dechant, M. Frotscher, and Y.-A. Barde (2002)
J. Neurosci. 22, 2409-2418
 |  Abstract »  |  Full Text »  |  PDF »

Neuronal nicotinic acetylcholine receptors: involvement in Alzheimer's disease and schizophrenia..

D. S. Woodruff-Pak and T. J. Gould (2002)
Behav Cogn Neurosci Rev 1, 5-20
 |  Abstract »  |  PDF »

Aging Causes a Preferential Loss of Cholinergic Innervation of Characterized Neocortical Pyramidal Neurons.

M. A. Casu, T. Pan Wong, Y. De Koninck, A. Ribeiro-da-Silva, and A. C. Cuello (2002)
Cereb Cortex 12, 329-337
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Central Inhibitory Muscarinic Autoreceptors by the Use of Muscarinic Acetylcholine Receptor Knock-Out Mice.

W. Zhang, A. S. Basile, J. Gomeza, L. A. Volpicelli, A. I. Levey, and J. Wess (2002)
J. Neurosci. 22, 1709-1717
 |  Abstract »  |  Full Text »  |  PDF »

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid.

J. Liu, E. Head, A. M. Gharib, W. Yuan, R. T. Ingersoll, T. M. Hagen, C. W. Cotman, and B. N. Ames (2002)
PNAS 99, 2356-2361
 |  Abstract »  |  Full Text »  |  PDF »

Scopolamine Enhances Generalization between Odor Representations in Rat Olfactory Cortex.

D. A. Wilson (2001)
Learn. Mem. 8, 279-285
 |  Abstract »  |  Full Text »  |  PDF »

Hyperactivity and Intact Hippocampus-Dependent Learning in Mice Lacking the M1 Muscarinic Acetylcholine Receptor.

T. Miyakawa, M. Yamada, A. Duttaroy, and J. Wess (2001)
J. Neurosci. 21, 5239-5250
 |  Abstract »  |  Full Text »  |  PDF »

Behavior and treatment in frontotemporal dementia.

R. J. Perry and B. L. Miller (2001)
Neurology 56, S46-51
 |  Abstract »  |  Full Text »  |  PDF »

Cholinergic Modulation of Excitatory Synaptic Transmission in the CA3 Area of the Hippocampus.

K. E. Vogt and W. G. Regehr (2001)
J. Neurosci. 21, 75-83
 |  Abstract »  |  Full Text »  |  PDF »

Muscarinic Cholinergic Modulation of Prepulse Inhibition of the Acoustic Startle Reflex.

C. K. Jones and H. E. Shannon (2000)
J. Pharmacol. Exp. Ther. 294, 1017-1023
 |  Abstract »  |  Full Text »

Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension.

M. A. Raskind, E. R. Peskind, T. Wessel, and W. Yuan (2000)
Neurology 54, 2261-2268
 |  Abstract »  |  Full Text »  |  PDF »

Further Evidence for a Dissociation Between Different Forms of Mnemonic Expressions in a Mouse Model of Age-related Cognitive Decline: Effects of Tacrine and S 17092, a Novel Prolyl Endopeptidase Inhibitor.

A. Marighetto, K. Touzani, N. Etchamendy, C. C. Torrea, G. De Nanteuil, D. Guez, R. Jaffard, and P. Morain (2000)
Learn. Mem. 7, 159-169
 |  Abstract »  |  Full Text »

Nerve Growth Factor (NGF) Augments Cortical and Hippocampal Cholinergic Functioning after p75NGF Receptor-Mediated Deafferentation But Impairs Inhibitory Avoidance and Induces Fear-Related Behaviors.

J. Winkler, G. A. Ramirez, L. J. Thal, and J. J. Waite (2000)
J. Neurosci. 20, 834-844
 |  Abstract »  |  Full Text »  |  PDF »

Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation.

L. Lin, B. Georgievska, A. Mattsson, and O. Isacson (1999)
PNAS 96, 12108-12113
 |  Abstract »  |  Full Text »  |  PDF »

Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy.

D. E. Smith, J. Roberts, F. H. Gage, and M. H. Tuszynski (1999)
PNAS 96, 10893-10898
 |  Abstract »  |  Full Text »  |  PDF »

Basal forebrain amnesia: does the nucleus accumbens contribute to human memory?.

G. Goldenberg, U. Schuri, O. Gromminger, and U. Arnold (1999)
J. Neurol. Neurosurg. Psychiatry 67, 163-168
 |  Abstract »  |  Full Text »  |  PDF »

Improved Cognition in Alzheimer's Disease With Short-Term D-Cycloserine Treatment.

G. E. Tsai, W. E. Falk, J. Gunther, and J. T. Coyle (1999)
Am J Psychiatry 156, 467-469
 |  Abstract »  |  Full Text »

In vivo mapping of cerebral acetylcholinesterase activity in aging and Alzheimer's disease.

D. E. Kuhl, R. A. Koeppe, S. Minoshima, S. E. Snyder, E. P. Ficaro, N. L. Foster, K. A. Frey, and M. R. Kilbourn (1999)
Neurology 52, 691
 |  Abstract »  |  Full Text »  |  PDF »

Improving Effects of Huperzine A on Spatial Working Memory in Aged Monkeys and Young Adult Monkeys with Experimental Cognitive Impairment.

J. W. Ye, J. X. Cai, L. M. Wang, and X. C. Tang (1999)
J. Pharmacol. Exp. Ther. 288, 814-819
 |  Abstract »  |  Full Text »

ONO-1603, a Potential Antidementia Drug, Delays Age-Induced Apoptosis and Suppresses Overexpression of Glyceraldehyde-3-Phosphate Dehydrogenase in Cultured Central Nervous System Neurons.

N. Katsube, K. Sunaga, H. Aishita, D.-M. Chuang, and R. Ishitani (1999)
J. Pharmacol. Exp. Ther. 288, 6-13
 |  Abstract »  |  Full Text »

Dexamethasone Induces Hypertrophy of Developing Medial Septum Cholinergic Neurons: Potential Role of Nerve Growth Factor.

B. Shi, S. J. Rabin, C. Brandoli, and I. Mocchetti (1998)
J. Neurosci. 18, 9326-9334
 |  Abstract »  |  Full Text »  |  PDF »

beta -Adrenergic receptor-induced activation of nerve growth factor gene transcription in rat cerebral cortex involves CCAAT/enhancer-binding protein delta.

A. M. Colangelo, P. F. Johnson, and I. Mocchetti (1998)
PNAS 95, 10920-10925
 |  Abstract »  |  Full Text »  |  PDF »

Cholinergic Switching Within Neocortical Inhibitory Networks.

Z. Xiang, J. R. Huguenard, and D. A. Prince (1998)
Science 281, 985-988
 |  Abstract »  |  Full Text »

Increased Calcium Buffering in Basal Forebrain Neurons During Aging.

D. Murchison and W. H. Griffith (1998)
J Neurophysiol 80, 350-364
 |  Abstract »  |  Full Text »  |  PDF »

Estrogen Therapy in Postmenopausal Women: Effects on Cognitive Function and Dementia.

K. Yaffe, G. Sawaya, I. Lieberburg, and D. Grady (1998)
JAMA 279, 688-695
 |  Abstract »  |  Full Text »  |  PDF »

Effects of U-50,488H on Scopolamine-, Mecamylamine- and Dizocilpine-Induced Learning and Memory Impairment in Rats.

M. Hiramatsu, H. Murasawa, T. Nabeshima, and T. Kameyama (1998)
J. Pharmacol. Exp. Ther. 284, 858-867
 |  Abstract »  |  Full Text »

Neurosteroids: Deficient cognitive performance in aged rats depends on low pregnenolone sulfate levels in the hippocampus.

M. Vallee, W. Mayo, M. Darnaudery, C. Corpechot, J. Young, M. Koehl, M. Le Moal, E.-E. Baulieu, P. Robel, and H. Simon (1997)
PNAS 94, 14865-14870
 |  Abstract »  |  Full Text »  |  PDF »

Peroxide Modulation of Slow Onset Potentiation in Rat Hippocampus.

J. M. Auerbach and M. Segal (1997)
J. Neurosci. 17, 8695-8701
 |  Abstract »  |  Full Text »  |  PDF »

Cerebral cortical astroglia from the trisomy 16 mouse, a model for Down syndrome, produce neuronal cholinergic deficits in cell culture.

P. G. Nelson, S. Fitzgerald, S. I. Rapoport, E. A. Neale, Z. Galdzicki, V. Dunlap, L. Bowers, and D. v. Agoston (1997)
PNAS 94, 12644-12648
 |  Abstract »  |  Full Text »  |  PDF »

Life and Death of Neurons in the Aging Brain.

J. H. Morrison and P. R. Hof (1997)
Science 278, 412-419
 |  Abstract »  |  Full Text »

A Role for TrkA during Maturation of Striatal and Basal Forebrain Cholinergic Neurons In Vivo.

A. M. Fagan, M. Garber, M. Barbacid, I. Silos-Santiago, and D. M. Holtzman (1997)
J. Neurosci. 17, 7644-7654
 |  Abstract »  |  Full Text »  |  PDF »

ABT-089 [2-Methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A Potent and Selective Cholinergic Channel Modulator with Neuroprotective Properties.

J. P. Sullivan, D. Donnelly-Roberts, C. A. Briggs, D. J. Anderson, M. Gopalakrishnan, I. C. Xue, M. Piattoni-Kaplan, E. Molinari, J. E. Campbell, D. G. Mckenna, et al. (1997)
J. Pharmacol. Exp. Ther. 283, 235-246
 |  Abstract »  |  Full Text »

ABT-089 [2-Methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A Novel Cholinergic Channel Modulator with Effects on Cognitive Performance in Rats and Monkeys.

M. W. Decker, A. W. Bannon, P. Curzon, K. L. Gunther, J. D. Brioni, M. W. Holladay, N.-H. Lin, Y. Li, J. F. Daanen, J. J. Buccafusco, et al. (1997)
J. Pharmacol. Exp. Ther. 283, 247-258
 |  Abstract »  |  Full Text »

Regulation of Human alpha 4beta 2 Neuronal Nicotinic Acetylcholine Receptors by Cholinergic Channel Ligands and Second Messenger Pathways.

M. Gopalakrishnan, E. J. Molinari, and J. P. Sullivan (1997)
Mol. Pharmacol. 52, 524-534
 |  Abstract »  |  Full Text »

Effects of Xanomeline, a Selective Muscarinic Receptor Agonist, on Cognitive Function and Behavioral Symptoms in Alzheimer Disease.

N. C. Bodick, W. W. Offen, A. I. Levey, N. R. Cutler, S. G. Gauthier, A. Satlin, H. E. Shannon, G. D. Tollefson, K. Rasmussen, F. P. Bymaster, et al. (1997)
Arch Neurol 54, 465-473
 |  Abstract »  |  PDF »

FK960 [N-(4-Acetyl-1-piperazinyl)-p-fluorobenzamide Monohydrate], a Novel Potential Antidementia Drug, Improves Visual Recognition Memory in Rhesus Monkeys: Comparison with Physostigmine.

N. Matsuoka and T. G. Aigner (1997)
J. Pharmacol. Exp. Ther. 280, 1201-1209
 |  Abstract »  |  Full Text »

Neurochemical Effects of 3-[1-(Phenylmethyl)-4-Piperidinyl]-1-(2,3,4,5-Tetrahydro-1H-1-Benzazepin-8-yl)-1-Propanone Fumarate (TAK-147), a Novel Acetylcholinesterase Inhibitor, in Rats.

K. Hirai, K. Kato, T. Nakayama, H. Hayako, Y. Ishihara, G. Goto, and M. Miyamoto (1997)
J. Pharmacol. Exp. Ther. 280, 1261-1269
 |  Abstract »  |  Full Text »

Pharmacological Activity and Safety Profile of P10358, a Novel, Orally Active Acetylcholinesterase Inhibitor for Alzheimer's Disease.

C. P. Smith, G. M. Bores, W. Petko, M. Li, D. E. Selk, D. K. Rush, F. Camacho, J. T. Winslow, R. Fishkin, D. M. Cunningham, et al. (1997)
J. Pharmacol. Exp. Ther. 280, 710-720
 |  Abstract »  |  Full Text »

Modulation of Inhibitory Transmission by Dopamine in Rat Basal Forebrain Nuclei: Activation of Presynaptic D1-like Dopaminergic Receptors.

T. Momiyama and J. A. Sim (1996)
J. Neurosci. 16, 7505-7512
 |  Abstract »  |  Full Text »  |  PDF »

Muscarinic acetylcholine receptor expression in memory circuits: Implications for treatment of Alzheimer disease.

A. I. Levey (1996)
PNAS 93, 13541-13546
 |  Abstract »  |  Full Text »  |  PDF »

Estrogen Replacement Therapy and Risk of Alzheimer Disease.

A. Paganini-Hill and V. W. Henderson (1996)
Arch Intern Med 156, 2213-2217
 |  Abstract »  |  PDF »

Cholinergic Changes in the Hippocampus of Stroke-Prone Spontaneously Hypertensive Rats.

H. Togashi, S. Kimura, M. Matsumoto, M. Yoshioka, M. Minami, and H. Saito (1996)
Stroke 27, 520-526
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A Signaling Endosome Hypothesis to Explain NGF Actions: Potential Implications for Neurodegeneration.

E.C. Beattie, J. Zhou, M.L. Grimes, N.W. Bunnett, C.L. Howe, and W.C. Mobley (1996)
Cold Spring Harb Symp Quant Biol 61, 389-406
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Cognitive Test Performance in Detecting, Staging, and Tracking Alzheimer's Disease.

J. J. Locascio, J. H. Growdon, and S. Corkin (1995)
Arch Neurol 52, 1087-1099
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Biologic Markers and Neurochemical Correlates of Agitation and Psychosis in Dementia.

M. Kirby and B. A. Lawlor (1995)
J Geriatr Psychiatry Neurol 8, S2-S7
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The treatment of Alzheimer's disease.

N.H.P. Allen and A. Burns (1995)
J Psychopharmacol 9, 43-56
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Estrogen Replacement Therapy in Older Women: Comparisons Between Alzheimer's Disease Cases and Nondemented Control Subjects.

V. W. Henderson, A. Paganini-Hill, C. K. Emanuel, M. E. Dunn, and J. G. Buckwalter (1994)
Arch Neurol 51, 896-900
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Quantitative EEG During a Double-Blind Trial of THA and Lecithin in Patients with Alzheimer's Disease.

K. M. Perryman and L. J. Fitten (1991)
J Geriatr Psychiatry Neurol 4, 127-133
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Intracerebroventricular Bethanechol for Alzheimer's Disease: Variable Dose-Related Responses.

S. L. Read, J. Frazee, J. Shapira, C. Smith, J. L. Cummings, and U. Tomiyasu (1990)
Arch Neurol 47, 1025-1030
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Induction of Alzheimer Antigens by an Uncoupler of Oxidative Phosphorylation.

J. P. Blass, A. C. Baker, L.-w. Ko, and R. S. Black (1990)
Arch Neurol 47, 864-869
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Associative Memory Function in Piriform (Olfactory) Cortex: Computational Modeling and Neuropharmacology.

M.E. Hasselmo, M.A. Wilson, B.R. Anderson, and J.M. Bower (1990)
Cold Spring Harb Symp Quant Biol 55, 599-610
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Studies of Transketolase Abnormality in Alzheimer's Disease.

K.-F. R. Sheu, D. D. Clarke, Y.-T. Kim, J. P. Blass, B. J. Harding, and J. DeCicco (1988)
Arch Neurol 45, 841-845
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Brain Amyloid and Alzheimer Disease.

H. V. Vinters, B. L. Miller, and W. M. Pardridge (1988)
Ann Intern Med 109, 41-54
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A Preliminary Study of Carbamazepine in the Treatment of Assaultive Patients With Dementia.

J. F. Patterson (1988)
J Geriatr Psychiatry Neurol 1, 21-23
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Effects of Intravenous Physostigmine and Lecithin on Memory Loss in Multiple Sclerosis: Report of a Pilot Study.

G. J. Leo and S. M. Rao (1988)
Neurorehabil Neural Repair 2, 123-129
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Long-term neuropathological and neurochemical effects of nucleus basalis lesions in the rat.

G. Arendash, W. Millard, A. Dunn, and E. Meyer (1987)
Science 238, 952-956
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