Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 4 March 1983:
Vol. 219. no. 4588, pp. 1091 - 1093
DOI: 10.1126/science.6681679
Prev | Table of Contents | Next

Articles

Science, Vol 219, Issue 4588, 1091-1093
Copyright © 1983 by American Association for the Advancement of Science

articles

Coping and the stress-induced potentiation of stimulant stereotypy in the rat

AJ MacLennan and SF Maier

It has been shown that stressed rats display increased stereotypy in response to a subsequent amphetamine challenge. Evidence is presented showing that stress potentiates cocaine stereotypy as well. These effects of stress were found to be particular to stress that could not be controlled in that rats receiving an identical amount of stress from footshock, but allowed to control its duration, displayed no more stereotypy than did nonstressed rats. These findings have implications for the role of stress and coping in amphetamine and cocaine psychoses, endogenous psychoses, and some forms of schizophrenia.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Behavioral Characterization of Mice Lacking Histamine H3 Receptors.
H. Toyota, C. Dugovic, M. Koehl, A. D. Laposky, C. Weber, K. Ngo, Y. Wu, D. H. Lee, K. Yanai, E. Sakurai, et al. (2002)
Mol. Pharmacol. 62, 389-397
   Abstract »    Full Text »    PDF »
Incentive Sensitization by Previous Amphetamine Exposure: Increased Cue-Triggered "Wanting" for Sucrose Reward.
C. L. Wyvell and K. C. Berridge (2001)
J. Neurosci. 21, 7831-7840
   Abstract »    Full Text »    PDF »
Different effect of desipramine on locomotor activity in quinpiroletreated rats after repeated restraint and chronic mild stress.
P. S. D'Aquila, A. T. Peana, V. Carboni, and G. Serra (2000)
J Psychopharmacol 14, 347-352
   Abstract »    PDF »
An infection-based model of neurodevelopmental damage.
M. Hornig, H. Weissenbock, N. Horscroft, and W. I. Lipkin (1999)
PNAS 96, 12102-12107
   Abstract »    Full Text »    PDF »
Corticosterone Facilitates the Acquisition of Cocaine Self-Administration in Rats: Opposite Effects of the Type II Glucocorticoid Receptor Agonist Dexamethasone.
J. R. Mantsch, D. Saphier, and N. E. Goeders (1998)
J. Pharmacol. Exp. Ther. 287, 72-80
   Abstract »    Full Text »
Psychobiologic Mechanisms of Posttraumatic Stress Disorder.
D. S. Charney, A. Y. Deutch, J. H. Krystal, S. M. Southwick, and M. Davis (1993)
Arch Gen Psychiatry 50, 294-305
   Abstract »    PDF »
The Effect of Social Skills, Values, Peers, and Depression on Adolescent Substance Use.
R. L. Simons, L. B. Whitbeck, R. D. Conger, and J. N. Melby (1991)
The Journal of Early Adolescence 11, 466-481
   Abstract »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)