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Science 25 February 1983:
Vol. 219. no. 4587, pp. 987 - 988
DOI: 10.1126/science.6297010
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Articles

Science, Vol 219, Issue 4587, 987-988
Copyright © 1983 by American Association for the Advancement of Science

articles

Ammonium chloride prevents lytic growth of reovirus and helps to establish persistent infection in mouse L cells

WM Canning and BN Fields

Ammonium chloride, a lysosomotropic agent that raises intralysosomal pH, reduces the yield of reovirus during infection of mouse L cells. Subsequent removal of ammonium chloride results in the rapid establishment of a persistent infection.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Inhibition of Endosome-Lysosome System Acidification Enhances Porcine Circovirus 2 Infection of Porcine Epithelial Cells.
G. Misinzo, P. L. Delputte, and H. J. Nauwynck (2008)
J. Virol. 82, 1128-1135
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Regulation of polymeric immunoglobulin receptor expression by reovirus.
K. Pal, C. S. Kaetzel, K. Brundage, C. A. Cunningham, and C. F. Cuff (2005)
J. Gen. Virol. 86, 2347-2357
   Abstract »    Full Text »    PDF »
Cathepsin S Supports Acid-independent Infection by Some Reoviruses.
J. W. Golden, J. A. Bahe, W. T. Lucas, M. L. Nibert, and L. A. Schiff (2004)
J. Biol. Chem. 279, 8547-8557
   Abstract »    Full Text »    PDF »
Addition of Exogenous Protease Facilitates Reovirus Infection in Many Restrictive Cells.
J. W. Golden, J. Linke, S. Schmechel, K. Thoemke, and L. A. Schiff (2002)
J. Virol. 76, 7430-7443
   Abstract »    Full Text »    PDF »
Sites and Determinants of Early Cleavages in the Proteolytic Processing Pathway of Reovirus Surface Protein {sigma}3.
J. Jane-Valbuena, L. A. Breun, L. A. Schiff, and M. L. Nibert (2002)
J. Virol. 76, 5184-5197
   Abstract »    Full Text »    PDF »
Virion Disassembly Is Required for Apoptosis Induced by Reovirus.
J. L. Connolly and T. S. Dermody (2002)
J. Virol. 76, 1632-1641
   Abstract »    Full Text »    PDF »
Reovirus Virion-Like Particles Obtained by Recoating Infectious Subvirion Particles with Baculovirus-Expressed sigma 3 Protein: an Approach for Analyzing sigma 3 Functions during Virus Entry.
J. Jané-Valbuena, M. L. Nibert, S. M. Spencer, S. B. Walker, T. S. Baker, Y. Chen, V. E. Centonze, and L. A. Schiff (1999)
J. Virol. 73, 2963-2973
   Abstract »    Full Text »


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