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Science 25 February 1983:
Vol. 219. no. 4587, pp. 983 - 985
DOI: 10.1126/science.6823562

Articles

Science, Vol 219, Issue 4587, 983-985
Copyright © 1983 by American Association for the Advancement of Science


articles

Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

DR Senger, SJ Galli, AM Dvorak, CA Perruzzi, VS Harvey, and HF Dvorak

Tumor ascites fluids from guinea pigs, hamsters, and mice contain activity that rapidly increases microvascular permeability. Similar activity is also secreted by these tumor cells and a variety of other tumor cell lines in vitro. The permeability-increasing activity purified from either the culture medium or ascites fluid of one tumor, the guinea pig line 10 hepatocarcinoma, is a 34,000- to 42,000-dalton protein distinct from other known permeability factors.


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Albendazole: a Potent Inhibitor of Vascular Endothelial Growth Factor and Malignant Ascites Formation in OVCAR-3 Tumor-Bearing Nude Mice..
M. Hossein Pourgholami, Z. Yan Cai, Y. Lu, L. Wang, and D. Lawson Morris (2006)
Clin. Cancer Res. 12, 1928-1935
   Abstract »    Full Text »    PDF »
Targeting Angiogenesis With Integrative Cancer Therapies.
D. R. Yance Jr and S. M. Sagar (2006)
Integr Cancer Ther 5, 9-29
   Abstract »    PDF »
Peptides selected for binding to clotted plasma accumulate in tumor stroma and wounds.
J. Pilch, D. M. Brown, M. Komatsu, T. A. H. Jarvinen, M. Yang, D. Peters, R. M. Hoffman, and E. Ruoslahti (2006)
PNAS 103, 2800-2804
   Abstract »    Full Text »    PDF »
Review of the Effects of Anti-Angiogenic Compounds on the Epiphyseal Growth Plate.
A. P. Hall, F. R. Westwood, and P. F. Wadsworth (2006)
Toxicol Pathol 34, 131-147
   Abstract »    Full Text »    PDF »
Effect of Inhibition of Vascular Endothelial Growth Factor Signaling on Distribution of Extravasated Antibodies in Tumors.
T. Nakahara, S. M. Norberg, D. R. Shalinsky, D. D. Hu-Lowe, and D. M. McDonald (2006)
Cancer Res. 66, 1434-1445
   Abstract »    Full Text »    PDF »
Overcoming Physiologic Barriers to Cancer Treatment by Molecularly Targeting the Tumor Microenvironment.
R. Cairns, I. Papandreou, and N. Denko (2006)
Mol. Cancer Res. 4, 61-70
   Abstract »    Full Text »    PDF »
Vascular endothelial growth factor in the lung.
N. F. Voelkel, R. W. Vandivier, and R. M. Tuder (2006)
Am J Physiol Lung Cell Mol Physiol 290, L209-L221
   Abstract »    Full Text »    PDF »
Proteomic Analysis of Malignant Ovarian Cancer Effusions as a Tool for Biologic and Prognostic Profiling.
B. Davidson, V. Espina, S. M. Steinberg, V. A. Florenes, L. A. Liotta, G. B. Kristensen, C. G. Trope, A. Berner, and E. C. Kohn (2006)
Clin. Cancer Res. 12, 791-799
   Abstract »    Full Text »    PDF »
Influence of Treatment Parameters on Selectivity of Verteporfin Therapy.
S. Michels, F. Hansmann, W. Geitzenauer, and U. Schmidt-Erfurth (2006)
Invest. Ophthalmol. Vis. Sci. 47, 371-376
   Abstract »    Full Text »    PDF »
Vascular endothelial growth factor increases the ultrafiltration coefficient in isolated intact Wistar rat glomeruli.
A. H. J. Salmon, C. R. Neal, D. O. Bates, and S. J. Harper (2006)
J. Physiol. 570, 141-156
   Abstract »    Full Text »    PDF »
Antitumor Vascular Strategy for Controlling Experimental Metastatic Spread of Human Small-Cell Lung Cancer Cells with ZD6474 in Natural Killer Cell-Depleted Severe Combined Immunodeficient Mice.
S. Yano, H. Muguruma, Y. Matsumori, H. Goto, E. Nakataki, N. Edakuni, H. Tomimoto, S. Kakiuchi, A. Yamamoto, H. Uehara, et al. (2005)
Clin. Cancer Res. 11, 8789-8798
   Abstract »    Full Text »    PDF »
Errors of measurement for blood volume parameters: a meta-analysis.
C. J. Gore, W. G. Hopkins, and C. M. Burge (2005)
J Appl Physiol 99, 1745-1758
   Abstract »    Full Text »    PDF »
RS3PE syndrome presenting as vascular endothelial growth factor associated disorder.
K Arima, T Origuchi, M Tamai, N Iwanaga, Y Izumi, M Huang, F Tanaka, M Kamachi, K Aratake, H Nakamura, et al. (2005)
Ann Rheum Dis 64, 1653-1655
   Abstract »    Full Text »    PDF »
Vascular Endothelial Growth Factor-A Promotes Peritumoral Lymphangiogenesis and Lymphatic Metastasis.
M. A. Bjorndahl, R. Cao, J. B. Burton, E. Brakenhielm, P. Religa, D. Galter, L. Wu, and Y. Cao (2005)
Cancer Res. 65, 9261-9268
   Abstract »    Full Text »    PDF »
Response of a Nonmalignant Pleural Effusion to Bevacizumab.
O. Pichelmayer, C. Zielinski, and M. Raderer (2005)
N. Engl. J. Med. 353, 740-741
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Inhibition of Vascular Permeability Factor/Vascular Endothelial Growth Factor-mediated Angiogenesis by the Kruppel-like Factor KLF2.
R. Bhattacharya, S. SenBanerjee, Z. Lin, S. Mir, A. Hamik, P. Wang, P. Mukherjee, D. Mukhopadhyay, and M. K. Jain (2005)
J. Biol. Chem. 280, 28848-28851
   Abstract »    Full Text »    PDF »



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