Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 11 February 1983:
Vol. 219. no. 4585, pp. 632 - 637
DOI: 10.1126/science.6337396

Articles

Science, Vol 219, Issue 4585, 632-637
Copyright © 1983 by American Association for the Advancement of Science


articles

Human insulin from recombinant DNA technology

IS Johnson

Human insulin produced by recombinant DNA technology is the first commercial health care product derived from this technology. Work on this product was initiated before there were federal guidelines for large-scale recombinant DNA work or commercial development of recombinant DNA products. The steps taken to facilitate acceptance of large-scale work and proof of the identity and safety of such a product are described. While basic studies in recombinant DNA technology will continue to have a profound impact on research in the life sciences, commercial applications may well be controlled by economic conditions and the availability of investment capital.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Kernel energy method: Application to insulin.
L. Huang, L. Massa, and J. Karle (2005)
PNAS 102, 12690-12693
   Abstract »    Full Text »    PDF »
Biotechnology in pharmaceuticals: the Japanese challenge.
M. Dibner (1985)
Science 229, 1230-1235
   Abstract »    PDF »
Recombinant DNA and Endocrine Therapy in Children.
M. S. Kappy, G. S. Stein, and J. L. Stein (1983)
Arch Pediatr Adolesc Med 137, 685-690
   Abstract »    PDF »
Rabies virus glycoprotein analogs: biosynthesis in Escherichia coli.
E Yelverton, S Norton, J. Obijeski, and D. Goeddel (1983)
Science 219, 614-620
   Abstract »    PDF »



To Advertise     Find Products


Science. ISSN 0036-8075 (print), 1095-9203 (online)