Science, Vol 218, Issue 4575, 904-906
Copyright © 1982 by American Association for the Advancement of Science
Sex preselection in mammals? Separation of sperm bearing Y and "O" chromosomes in the vole Microtus oregoni
D Pinkel,
BL Gledhill,
S Lake,
D Stephenson,
and
MA Van Dilla
The two sex determining sperm populations of the vole Microtus oregoni were separated according to DNA content by use of flow sorting instrumentation. Although the sperm were not viable, they should be useful for addressing the question of haploid expression of genes linked to sex chromosomes and for efficiently searching for biochemical markers that differentiate the two populations.