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Science 29 October 1982:
Vol. 218. no. 4571, pp. 493 - 494
DOI: 10.1126/science.7123252
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Articles

Science, Vol 218, Issue 4571, 493-494
Copyright © 1982 by American Association for the Advancement of Science

articles

Prenatal and neonatal exposure to cimetidine results in gonadal and sexual dysfunction in adult males

S Anand and DH Van Thiel

Exposure of rats to cimetidine during intrauterine life and the immediate neonatal period results in hypoandrogenization in adult life with decreased weights of androgen-dependent tissues and decreased concentrations of testosterone. Moreover, sexual behavior patterns in adult life are disturbed as shown by a lack of sexual motivation and decreased performance.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Detection of Effects on Male Reproduction--A Literature Survey.
B. Ulbrich and A. K. Palmer (1995)
International Journal of Toxicology 14, 293-327
   Abstract »    PDF »
Perinatal dopamine-related drugs demasculinize rats.
E. Hull, J. Nishita, D Bitran, and S Dalterio (1984)
Science 224, 1011-1013
   Abstract »    PDF »


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