Science, Vol 218, Issue 4571, 490-491
Copyright © 1982 by American Association for the Advancement of Science
Sugar infusion can enhance feeding
PJ Geiselman
and
D Novin
An investigation was made of the role of glucose in the regulation of hunger and satiety in the rabbit. Glucose, when infused intraduodenally at a low rate (1 milliliter per minute), produced a decrease in food intake. However, when glucose was infused into the duodenum at a high rate (3 milliliters per minute), the rabbits nearly doubled their food intake during the first half-hour after infusion. It is hypothesized that the rapid arrival and glucose in the duodenum may produce hunger.