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Science 24 September 1982:
Vol. 217. no. 4566, pp. 1272 - 1273
DOI: 10.1126/science.6287581
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Articles

Science, Vol 217, Issue 4566, 1272-1273
Copyright © 1982 by American Association for the Advancement of Science

articles

Naloxone antagonism of the thermoregulatory effects of phencyclidine

SD Glick and RA Guido

Phencyclidine elicits hyperthermia at low doses and hypothermia at high doses in rats. Naloxone antagonizes both effects. Phencyclidine's effects on thermo-regulation are probably mediated by an interaction with a mu opiate receptor.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)