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Science 13 August 1982:
Vol. 217. no. 4560, pp. 661 - 663
DOI: 10.1126/science.6124043
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Articles

Science, Vol 217, Issue 4560, 661-663
Copyright © 1982 by American Association for the Advancement of Science

articles

Destruction of noradrenergic neurons in rabbit brainstem elevates plasma vasopressin, causing hypertension

WW Blessing, AF Sved, and DJ Reis

When A1 noradrenergic neurons in the caudal ventrolateral medulla of rabbits are destroyed electrolytically or by local injection of the neurotoxin kainic acid, the concentration of vasopressin in plasma increases, causing hypertension. The A1 neurons may tonically inhibit the activity of vasopressin-secreting neuroendocrine cells through a direct hypothalamic projection.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Role of the Medulla Oblongata in Hypertension.
E. Colombari, M. A. Sato, S. L. Cravo, C. T. Bergamaschi, R. R. Campos Jr, and O. U. Lopes (2001)
Hypertension 38, 549-554
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)