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Science 2 July 1982:
Vol. 217. no. 4554, pp. 63 - 64
DOI: 10.1126/science.6283633
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Articles

Science, Vol 217, Issue 4554, 63-64
Copyright © 1982 by American Association for the Advancement of Science

articles

Rat pro-opiomelanocortin contains sulfate

H Hoshina, G Hortin, and I Boime

Intermediate lobes isolated from rat pituitary glands incorporated [35S]sulfate into pro-opiomelanocortin and other adrenocorticotropic hormone-containing peptides. Incubation of intermediate lobes in medium containing the arginine analog canavanine inhibited the cleavage of pro-opiomelanocortin into smaller products. Pro-opiomelanocortin that accumulated in the presence of canavanine was also sulfated.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Distinct Molecular Events during Secretory Granule Biogenesis Revealed by Sensitivities to Brefeldin A.
C. J. Fernandez, M. Haugwitz, B. Eaton, and H.-P. H. Moore (1997)
Mol. Biol. Cell 8, 2171-2185
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Science. ISSN 0036-8075 (print), 1095-9203 (online)