Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 18 June 1982:
Vol. 216. no. 4552, pp. 1325 - 1327
DOI: 10.1126/science.7079765
Prev | Table of Contents | Next

Articles

Science, Vol 216, Issue 4552, 1325-1327
Copyright © 1982 by American Association for the Advancement of Science

articles

Proton nuclear magnetic resonance of intact Friend leukemia cells: phosphorylcholine increase during differentiation

PF Agris and ID Campbell

Proton nuclear magnetic resonance of intact Friend leukemia cells was used to analyze their erythroid-like differentiation. The technique, which requires only 10(3) to 10(9) cells and approximately 2 minutes for acquisition of each spectrum, demonstrated the occurrence of many signal changes during differentiation. With cell extracts, 64 signals were assigned to 12 amino acids and 19 other intermediary metabolites, and a dramatic signal change was attributed to a fourfold increase in cytoplasmic phosphorylcholines.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Prostate Cancer: Sextant Localization with MR Imaging, MR Spectroscopy, and 11C-Choline PET/CT.
C. Testa, R. Schiavina, R. Lodi, E. Salizzoni, B. Corti, M. Farsad, J. Kurhanewicz, F. Manferrari, E. Brunocilla, C. Tonon, et al. (2007)
Radiology 244, 797-806
   Abstract »    Full Text »    PDF »
Proton MR Spectroscopy of Mitochondrial Diseases: Analysis of Brain Metabolic Abnormalities and Their Possible Diagnostic Relevance.
M. C. Bianchi, M. Tosetti, R. Battini, M. L. Manca, M. Mancuso, G. Cioni, R. Canapicchi, and G. Siciliano (2003)
AJNR Am. J. Neuroradiol. 24, 1958-1966
   Abstract »    Full Text »    PDF »
Phosphorous metabolites and steady-state energetics of transformed fibroblasts during three-dimensional growth.
L. A. Kunz-Schughart and J. P. Freyer (2002)
Am J Physiol Cell Physiol 283, C1287-C1297
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)