Science 11 June 1982: Vol. 216. no. 4551, pp. 1233 - 1235 DOI: 10.1126/science.6177045

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The Role of Zinc Finger Protein 521/Early Hematopoietic Zinc Finger Protein in Erythroid Cell Differentiation.

E. Matsubara, I. Sakai, J. Yamanouchi, H. Fujiwara, Y. Yakushijin, T. Hato, K. Shigemoto, and M. Yasukawa (2009)
J. Biol. Chem. 284, 3480-3487
 |  Abstract »  |  Full Text »  |  PDF »

Activity of TKI258 against primary cells and cell lines with FGFR1 fusion genes associated with the 8p11 myeloproliferative syndrome.

A. Chase, F. H. Grand, and N. C. P. Cross (2007)
Blood 110, 3729-3734
 |  Abstract »  |  Full Text »  |  PDF »

Coordination of intrinsic, extrinsic, and endoplasmic reticulum-mediated apoptosis by imatinib mesylate combined with arsenic trioxide in chronic myeloid leukemia.

Y. Du, K. Wang, H. Fang, J. Li, D. Xiao, P. Zheng, Y. Chen, H. Fan, X. Pan, C. Zhao, et al. (2006)
Blood 107, 1582-1590
 |  Abstract »  |  Full Text »  |  PDF »

Rare occurrence of the JAK2 V617F mutation in AML subtypes M5, M6, and M7.

S. Frohling, D. B. Lipka, S. Kayser, C. Scholl, R. F. Schlenk, H. Dohner, D. G. Gilliland, R. L. Levine, and K. Dohner (2006)
Blood 107, 1242-1243
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Homozygous JAK2 V617P Gain-of-Function Mutation Is Responsible for Constitutive JAK2/STAT5 Activation and Proliferation of HEL.92.1.7. Cell Line..

M. L. Estes, Y. Ozawa, A. H. Williams, A. F. List, and L. Sokol (2005)
Blood (ASH Annual Meeting Abstracts) 106, 4377
 |  Abstract »

Plasmodium falciparum rhoptry protein RSP2 triggers destruction of the erythroid lineage.

C. Layez, P. Nogueira, V. Combes, F. T. M. Costa, I. Juhan-Vague, L. H. P. da Silva, and J. Gysin (2005)
Blood 106, 3632-3638
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Ghrelin Is Produced by the Human Erythroleukemic HEL Cell Line and Involved in an Autocrine Pathway Leading to Cell Proliferation.

C. De Vriese, F. Gregoire, P. De Neef, P. Robberecht, and C. Delporte (2005)
Endocrinology 146, 1514-1522
 |  Abstract »  |  Full Text »  |  PDF »

Histidine-stimulated divalent metal uptake in human erythrocytes and in the erythroleukaemic cell line HEL.92.1.7.

F Oakley, N. M Horn, and A. L Thomas (2004)
J. Physiol. 561, 525-534
 |  Abstract »  |  Full Text »  |  PDF »

Differential Expression of Thromboxane Synthase in Prostate Carcinoma: Role in Tumor Cell Motility.

D. Nie, M. Che, A. Zacharek, Y. Qiao, L. Li, X. Li, M. Lamberti, K. Tang, Y. Cai, Y. Guo, et al. (2004)
Am. J. Pathol. 164, 429-439
 |  Abstract »  |  Full Text »  |  PDF »

DNase I Hypersensitivity Patterns of the Serglycin Proteoglycan Gene in Resting and Phorbol 12-Myristate 13-Acetate-stimulated Human Erythroleukemia (HEL), CHRF 288-11, and HL-60 Cells Compared with Neutrophils and Human Umbilical Vein Endothelial Cells.

P. Castronuevo, M. A. Thornton, L. E. McCarthy, J. Klimas, and B. P. Schick (2003)
J. Biol. Chem. 278, 48704-48712
 |  Abstract »  |  Full Text »  |  PDF »

Erythroid Differentiation Sensitizes K562 Leukemia Cells to TRAIL-Induced Apoptosis by Downregulation of c-FLIP.

V. Hietakangas, M. Poukkula, K. M. Heiskanen, J. T. Karvinen, L. Sistonen, and J. E. Eriksson (2003)
Mol. Cell. Biol. 23, 1278-1291
 |  Abstract »  |  Full Text »  |  PDF »

Validation of a Recombinant DNA Construct ({micro}LCR and Full-Length {beta}-Globin Gene) for Quantification of Human {beta}-Globin Expression: Application to Mutations in the Promoter, Intronic, and 5'- and 3'-Untranslated Regions of the Human {beta}-Globin Gene.

L. M. Irenge, M. Heusterspreute, M. Philippe, I. Derclaye, A. Robert, and J.-L. Gala (2002)
Clin. Chem. 48, 1787-1791
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A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo.

M. Levis, J. Allebach, K.-F. Tse, R. Zheng, B. R. Baldwin, B. D. Smith, S. Jones-Bolin, B. Ruggeri, C. Dionne, and D. Small (2002)
Blood 99, 3885-3891
 |  Abstract »  |  Full Text »  |  PDF »

A High-Capacity, Capsid-Modified Hybrid Adenovirus/Adeno-Associated Virus Vector for Stable Transduction of Human Hematopoietic Cells.

D. M. Shayakhmetov, C. A. Carlson, H. Stecher, Q. Li, G. Stamatoyannopoulos, and A. Lieber (2002)
J. Virol. 76, 1135-1143
 |  Abstract »  |  Full Text »  |  PDF »

Detection of Cyclin D1 Overexpression by Real-Time Reverse-Transcriptase-Mediated Quantitative Polymerase Chain Reaction for the Diagnosis of Mantle Cell Lymphoma.

R. Suzuki, K. Takemura, M. Tsutsumi, S. Nakamura, N. Hamajima, and M. Seto (2001)
Am. J. Pathol. 159, 425-429
 |  Abstract »  |  Full Text »

Interleukin-4 Downregulates Nuclear Factor-Erythroid 2 (NF-E2) Expression in Primary Megakaryocytes and in Megakaryoblastic Cell Lines.

L. Catani, M. Amabile, S. Luatti, L. Valdre, N. Vianelli, G. Martinelli, and S. Tura (2001)
Stem Cells 19, 339-347
 |  Abstract »  |  Full Text »  |  PDF »

Ionizing radiation sensitizes erythroleukemic cells but not normal erythroblasts to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by selective up-regulation of TRAIL-R1.

R. Di Pietro, P. Secchiero, R. Rana, D. Gibellini, G. Visani, K. Bemis, L. Zamai, S. Miscia, and G. Zauli (2001)
Blood 97, 2596-2603
 |  Abstract »  |  Full Text »  |  PDF »

Smad7 selectively interferes with different pathways of activin signaling and inhibits erythroid leukemia cell differentiation.

K. Kitamura, S.-i. Aota, R. Sakamoto, S.-I. Yoshikawa, and K. Okazaki (2000)
Blood 95, 3371-3379
 |  Abstract »  |  Full Text »  |  PDF »

Nitric oxide induces apoptosis in megakaryocytic cell lines.

E. Battinelli and J. Loscalzo (2000)
Blood 95, 3451-3459
 |  Abstract »  |  Full Text »  |  PDF »

Adherence of Human Erythroleukemia Cells Inhibits Proliferation without Inducing Differentiation.

A. Molla and M. R. Block (2000)
Cell Growth Differ. 11, 83-90
 |  Abstract »  |  Full Text »

Functional Characterization of the Human Platelet Glycoprotein V Gene Promoter: A Specific Marker of Late Megakaryocytic Differentiation.

A. Lepage, G. Uzan, N. Touche, M. Morales, J.-P. Cazenave, F. Lanza, and C. de la Salle (1999)
Blood 94, 3366-3380
 |  Abstract »  |  Full Text »  |  PDF »

Factor XI Messenger RNA in Human Platelets.

D. Martincic, V. Kravtsov, and D. Gailani (1999)
Blood 94, 3397-3404
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Necrosis Factor-alpha -induced Proliferation of Human Mo7e Leukemic Cells Occurs via Activation of Nuclear Factor kappa B Transcription Factor.

R. Y. Liu, C. Fan, N. E. Olashaw, X. Wang, and K. S. Zuckerman (1999)
J. Biol. Chem. 274, 13877-13885
 |  Abstract »  |  Full Text »  |  PDF »

Heparan Sulfate Proteoglycan Expression Is Induced During Early Erythroid Differentiation of Multipotent Hematopoietic Stem Cells.

Z. Drzeniek, G. Stocker, B. Siebertz, U. Just, T. Schroeder, W. Ostertag, and H.-D. Haubeck (1999)
Blood 93, 2884-2897
 |  Abstract »  |  Full Text »  |  PDF »

Constitutive Activation of the JAK2/STAT5 Signal Transduction Pathway Correlates With Growth Factor Independence of Megakaryocytic Leukemic Cell Lines.

R. Y. Liu, C. Fan, R. Garcia, R. Jove, and K. S. Zuckerman (1999)
Blood 93, 2369-2379
 |  Abstract »  |  Full Text »  |  PDF »

CD19 Is Linked to the Integrin-associated Tetraspans CD9, CD81, and CD82.

G. Horvath, V. Serru, D. Clay, M. Billard, C. Boucheix, and E. Rubinstein (1998)
J. Biol. Chem. 273, 30537-30543
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The Induction of Megakaryocyte Differentiation Is Accompanied by Selective Ser133 Phosphorylation of the Transcription Factor CREB in Both HEL Cell Line and Primary CD34+ Cells.

G. Zauli, D. Gibellini, M. Vitale, P. Secchiero, C. Celeghini, A. Bassini, S. Pierpaoli, M. Marchisio, L. Guidotti, and S. Capitani (1998)
Blood 92, 472-480
 |  Abstract »  |  Full Text »  |  PDF »

The MYND Motif Is Required for Repression of Basal Transcription from the Multidrug Resistance 1 Promoter by the t(8;21) Fusion Protein.

B. Lutterbach, D. Sun, J. Schuetz, and S. W. Hiebert (1998)
Mol. Cell. Biol. 18, 3604-3611
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PU.1 as an essential activator for the expression of gp91phox gene in human peripheral neutrophils, monocytes, and B lymphocytes.

S. Suzuki, A. Kumatori, I.-A. Haagen, Y. Fujii, M. A. Sadat, H. L. Jun, Y. Tsuji, D. Roos, and M. Nakamura (1998)
PNAS 95, 6085-6090
 |  Abstract »  |  Full Text »  |  PDF »

Differential expression of the Kell blood group and CD10 antigens: two related membrane metallopeptidases during differentiation of K562 cells by phorbol ester and hemin.

L. Maulon, S. Guérin, J. E. Ricci, Y. Colin, J. P. Cartron, and P. Auberger (1998)
FASEB J 12, 531-539
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Isolation of a cDNA Encoding a Novel Member of the Transglutaminase Gene Family from Human Keratinocytes. DETECTION AND IDENTIFICATION OF TRANSGLUTAMINASE GENE PRODUCTS BASED ON REVERSE TRANSCRIPTION-POLYMERASE CHAIN REACTION WITH DEGENERATE PRIMERS.

D. Aeschlimann, M. K. Koeller, B. L. Allen-Hoffmann, and D. F. Mosher (1998)
J. Biol. Chem. 273, 3452-3460
 |  Abstract »  |  Full Text »  |  PDF »

Neoexpression of the c-met/Hepatocyte Growth Factor-Scatter Factor Receptor Gene in Activated Monocytes.

M. Beilmann, M. Odenthal, W. Jung, G. F. Vande Woude, H.-P. Dienes, and P. Schirmacher (1997)
Blood 90, 4450-4458
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of the Apoptotic Response of Human Myeloid Leukemia Cells to a Diphtheria Toxin Granulocyte-Macrophage Colony-Stimulating Factor Fusion Protein.

A. E. Frankel, P. D. Hall, C. Burbage, J. Vesely, M. Willingham, K. Bhalla, and R. J. Kreitman (1997)
Blood 90, 3654-3661
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the Megakaryocyte-specific Gene Platelet Basic Protein (PBP) by the Ets Family Factor PU.1.

C. Zhang, P. Gadue, E. Scott, M. Atchison, and M. Poncz (1997)
J. Biol. Chem. 272, 26236-26246
 |  Abstract »  |  Full Text »  |  PDF »

Intergenic transcription and transinduction of the human beta -globin locus.

H. L. Ashe, J. Monks, M. Wijgerde, P. Fraser, and N. J. Proudfoot (1997)
Genes & Dev. 11, 2494-2509
 |  Abstract »  |  Full Text »  |  PDF »

Early Contamination of the Dami Cell Line by HEL.

R. A.F. MacLeod, W. G. Dirks, and H. G. Drexler (1997)
Blood 90, 2850
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Expression of Prostacyclin Receptor in Human Megakaryocytes.

Y. Sasaki, T. Takahashi, I. Tanaka, K. Nakamura, Y. Okuno, O. Nakagawa, S. Narumiya, and K. Nakao (1997)
Blood 90, 1039-1046
 |  Abstract »  |  Full Text »  |  PDF »

HLA-DR1-Restricted bcr-abl (b3a2)-Specific CD4+ T Lymphocytes Respond to Dendritic Cells Pulsed With b3a2 Peptide and Antigen-Presenting Cells Exposed to b3a2 Containing Cell Lysates.

S.I. Mannering, J.L. McKenzie, D.B. Fearnley, and D.N.J. Hart (1997)
Blood 90, 290-297
 |  Abstract »  |  Full Text »  |  PDF »

In Vitro Development of Erythroid and Megakaryocytic Cells From a UT-7 Subline, UT-7/GM.

N. Komatsu, K. Kirito, R. Shimizu, M. Kunitama, M. Yamada, M. Uchida, M. Takatoku, M. Eguchi, and Y. Miura (1997)
Blood 89, 4021-4033
 |  Abstract »  |  Full Text »  |  PDF »

The P2U Purinoceptor Obligatorily Engages the Heterotrimeric G Protein G16 to Mobilize Intracellular Ca2+ in Human Erythroleukemia Cells.

K. Baltensperger and H. Porzig (1997)
J. Biol. Chem. 272, 10151-10159
 |  Abstract »  |  Full Text »  |  PDF »

Effector Cell Protease Receptor-1, a Platelet Activation-dependent Membrane Protein, Regulates Prothrombinase-catalyzed Thrombin Generation.

B. A. Bouchard, C. S. Catcher, B. R. Thrash, C. Adida, and P. B. Tracy (1997)
J. Biol. Chem. 272, 9244-9251
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of DLX-7 homeobox gene causes decreased expression of GATA-1 and c-myc genes and apoptosis.

T. Shimamoto, S. Nakamura, J. Bollekens, F. H. Ruddle, and K. Takeshita (1997)
PNAS 94, 3245-3249
 |  Abstract »  |  Full Text »  |  PDF »

Structure and Expression of H-type GDP-L-Fucose:beta -D-Galactoside 2-alpha -L-Fucosyltransferase Gene (FUT1). TWO TRANSCRIPTION START SITES AND ALTERNATIVE SPLICING GENERATE SEVERAL FORMS OF FUT1 mRNA.

Y. Koda, M. Soejima, and H. Kimura (1997)
J. Biol. Chem. 272, 7501-7505
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Human Platelet/Endothelial Cell Adhesion Molecule-1 Promoter: Identification of a GATA-2 Binding Element Required for Optimal Transcriptional Activity.

R. J. Gumina, N. E. Kirschbaum, K. Piotrowski, and P. J. Newman (1997)
Blood 89, 1260-1269
 |  Abstract »  |  Full Text »  |  PDF »

Thrombopoietin Enhances the alpha IIbbeta 3-Dependent Adhesion of Megakaryocytic Cells to Fibrinogen or Fibronectin Through PI 3 Kinase.

G. Zauli, A. Bassini, M. Vitale, D. Gibellini, C. Celeghini, E. Caramelli, S. Pierpaoli, L. Guidotti, and S. Capitani (1997)
Blood 89, 883-895
 |  Abstract »  |  Full Text »  |  PDF »

Interferon Regulatory Factor-2 Directs Transcription from the gp91phox Promoter.

W. Luo and D. G. Skalnik (1996)
J. Biol. Chem. 271, 23445-23451
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of the Megakaryocyte Glycoprotein IX Promoter Identifies Positive and Negative Regulatory Domains and Functional GATA and Ets Sites.

L. S. Bastian, M. Yagi, C. Chan, and G. J. Roth (1996)
J. Biol. Chem. 271, 18554-18560
 |  Abstract »  |  Full Text »  |  PDF »

CCAAT Displacement Protein Competes with Multiple Transcriptional Activators for Binding to Four Sites in the Proximal gp91phox Promoter.

W. Luo and D. G. Skalnik (1996)
J. Biol. Chem. 271, 18203-18210
 |  Abstract »  |  Full Text »  |  PDF »

The Cell Cycle in Polyploid Megakaryocytes Is Associated with Reduced Activity of Cyclin B1-dependent Cdc2 Kinase.

Y. Zhang, Z. Wang, and K. Ravid (1996)
J. Biol. Chem. 271, 4266-4272
 |  Abstract »  |  Full Text »  |  PDF »

Desmoplakin expression and organization at human umbilical vein endothelial cell-to-cell junctions.

O Valiron, V Chevrier, Y Usson, F Breviario, D Job, and E Dejana (1996)
J. Cell Sci. 109, 2141-2149
 |  Abstract »  |  PDF »

Nuclear Factor Binding Sites in Human beta Globin IVS2.

C. E. Jackson, D. O' Neill, and A. Bank (1995)
J. Biol. Chem. 270, 28448-28456
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Essential GATA and Ets Binding Motifs within the Promoter of the Platelet Glycoprotein Ibalpha Gene.

Y. Hashimoto and J. Ware (1995)
J. Biol. Chem. 270, 24532-24539
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of a gp91-phox Promoter Element That Is Required for Interferon [IMAGE]-induced Transcription.

E. A. Eklund and D. G. Skalnik (1995)
J. Biol. Chem. 270, 8267-8273
 |  Abstract »  |  Full Text »  |  PDF »

Cerebral microenvironment influences expression of the vitronectin gene in astrocytic tumors.

C. Gladson, J. Wilcox, L Sanders, G. Gillespie, and D. Cheresh (1995)
J. Cell Sci. 108, 947-956
 |  Abstract »  |  PDF »

Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity.

P. Aplan, D. Lombardi, A. Ginsberg, J Cossman, V. Bertness, and I. Kirsch (1990)
Science 250, 1426-1429
 |  Abstract »  |  PDF »

Replication of the B19 parvovirus in human bone marrow cell cultures.

K Ozawa, G Kurtzman, and N Young (1986)
Science 233, 883-886
 |  Abstract »  |  PDF »

Transcriptional regulation of globin gene expression in the human erythroid cell line K562.

P Charnay and T Maniatis (1983)
Science 220, 1281-1283
 |  Abstract »  |  PDF »

Activation of p38 Mitogen-activated Protein Kinase Is Required for Tumor Necrosis Factor-alpha -supported Proliferation of Leukemia and Lymphoma Cell Lines.

R. Y. Liu, C. Fan, G. Liu, N. E. Olashaw, and K. S. Zuckerman (2000)
J. Biol. Chem. 275, 21086-21093
 |  Abstract »  |  Full Text »  |  PDF »

A Negative Cis-element Regulates the Level of Enhancement by Hypersensitive Site 2 of the beta -Globin Locus Control Region.

L. Elnitski, J. Li, C. T. Noguchi, W. Miller, and R. Hardison (2001)
J. Biol. Chem. 276, 6289-6298
 |  Abstract »  |  Full Text »  |  PDF »

The Matrix Attachment Region-binding Protein SATB1 Interacts with Multiple Elements within the gp91phox Promoter and Is Down-regulated during Myeloid Differentiation.

S. M. Hawkins, T. Kohwi-Shigematsu, and D. G. Skalnik (2001)
J. Biol. Chem. 276, 44472-44480
 |  Abstract »  |  Full Text »  |  PDF »

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