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Science 7 May 1982:
Vol. 216. no. 4546, pp. 646 - 647
DOI: 10.1126/science.6280284
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Articles

Science, Vol 216, Issue 4546, 646-647
Copyright © 1982 by American Association for the Advancement of Science

articles

High angiotensin-converting enzyme activity in the neurohypophysis of Brattleboro rats

C Chevillard and JM Saavedra

The activity of angiotensin-converting enzyme is significantly higher in the intermediate and posterior pituitary lobes of Brattleboro rats than in Long-Evans control rats. The high activity level was reversed by vasopressin treatment. Conversely, angiotensin-converting enzyme activity was significantly lower in the anterior pituitary of Brattleboro rats than in Long-Evans rats, and this activity level was not affected by vasopressin. these findings suggest an inverse relation between vasopressin and angiotensin systems in the posterior and intermediate lobes of the pituitary gland.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)