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Science 23 April 1982:
Vol. 216. no. 4544, pp. 437 - 439
DOI: 10.1126/science.7200261
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Articles

Science, Vol 216, Issue 4544, 437-439
Copyright © 1982 by American Association for the Advancement of Science

articles

Tumor rejection in rats after inescapable or escapable shock

MA Visintainer, Volpicelli JR, and ME Seligman

Rats experienced inescapable, escapable, or no electric shock 1 day after being implanted with a Walker 256 tumor preparation. Only 27 percent of the rats receiving inescapable shock rejected the tumor, whereas 63 percent of the rats receiving escapable shock and 54 percent of the rats receiving no shock rejected the tumor. These results imply that lack of control over stressors reduces tumor rejection and decreases survival.


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