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Science 23 April 1982:
Vol. 216. no. 4544, pp. 415 - 417
DOI: 10.1126/science.7071589
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Articles

Science, Vol 216, Issue 4544, 415-417
Copyright © 1982 by American Association for the Advancement of Science

articles

Systemic lupus erythematosus-like syndrome in monkeys fed alfalfa sprouts: role of a nonprotein amino acid

MR Malinow, EJ Bardana Jr, B Pirofsky, S Craig, and P McLaughlin

Hematologic and serologic abnormalities similar to those observed in human systemic lupus erythematosus (SLE) developed in cynomolgus macaques fed alfalfa sprouts. L-Canavanine sulfate, a constituent of alfalfa sprouts, was incorporated into the diet and reactivated the syndrome in monkeys in which an SLE-like syndrome had previously been induced by the ingestion of alfalfa seeds or sprouts.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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