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Science 16 April 1982:
Vol. 216. no. 4543, pp. 324 - 325
DOI: 10.1126/science.6801768

Articles

Science, Vol 216, Issue 4543, 324-325
Copyright © 1982 by American Association for the Advancement of Science


articles

Oxygen delivery to the brain before and after birth

MD Jones Jr, AA Rosenberg, MA Simmons, RA Molteni, RC Koehler, and RJ Traystman

We studied the relationship between cerebral oxygen consumption and cerebral oxygen delivery (cerebral blood flow x arterial oxygen content) in fetal, newborn, and adult sheep, Relative to the amount of oxygen consumed, cerebral oxygen delivery in the fetus exceeds that in the lamb and adult by 70 percent. This may represent a protective advantage for the fetus or simply a necessary adaptation to the low arterial oxygen pressure in the intrauterine environment.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Fetal cerebral blood flow, electrocorticographic activity, and oxygenation: responses to acute hypoxia.
S. J. Lee, D. P. Hatran, T. Tomimatsu, J. P. Peņa, G. McAuley, and L. D. Longo (2009)
J. Physiol. 587, 2033-2047
   Abstract »    Full Text »    PDF »
Fetal Hypercapnia in High-Altitude Acclimatized Sheep: Cerebral Blood Flow and Cerebral Oxygenation.
T. Tomimatsu, J. P. Pena, and L. D. Longo (2007)
Reproductive Sciences 14, 51-58
   Abstract »    PDF »
Cerebral blood flow and oxygenation in ovine fetus: responses to superimposed hypoxia at both low and high altitude.
J. P. Pena, T. Tomimatsu, D. P. Hatran, L. L. McGill, and L. D. Longo (2007)
J. Physiol. 578, 359-370
   Abstract »    Full Text »    PDF »



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