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Science 16 April 1982:
Vol. 216. no. 4543, pp. 313 - 315
DOI: 10.1126/science.6801766
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Articles

Science, Vol 216, Issue 4543, 313-315
Copyright © 1982 by American Association for the Advancement of Science

articles

Mycoplasma pneumoniae infection: role of a surface protein in the attachment organelle

PC Hu, RM Cole, YS Huang, JA Graham, DE Gardner, AM Collier, and WA Clyde Jr

Attachment of Mycoplasma pneumoniae to host cell by means of a specialized terminus initiates infection. Monoclonal antibodies to a surface protein (Pl) inhibit this process, and react with a region of the tip covered with peplomer-like particles. Since antibodies against the Pl protein are generated by natural and experimental infection and by immunization, the substance may be an important determinant of protective immunity.


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Genotyping analysis of Mycoplasma pneumoniae clinical strains in Japan between 1995 and 2005: type shift phenomenon of M. pneumoniae clinical strains.
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Synthesis, Stability, and Function of Cytadhesin P1 and Accessory Protein B/C Complex of Mycoplasma pneumoniae.
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Involvement of P1 Adhesin in Gliding Motility of Mycoplasma pneumoniae as Revealed by the Inhibitory Effects of Antibody under Optimized Gliding Conditions.
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Use of Fluorescent-Protein Tagging To Determine the Subcellular Localization of Mycoplasma pneumoniae Proteins Encoded by the Cytadherence Regulatory Locus.
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Spike Structure at the Interface between Gliding Mycoplasma mobile Cells and Glass Surfaces Visualized by Rapid-Freeze-and-Fracture Electron Microscopy.
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Identification of a 349-Kilodalton Protein (Gli349) Responsible for Cytadherence and Glass Binding during Gliding of Mycoplasma mobile.
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Attachment Organelle Formation Represented by Localization of Cytadherence Proteins and Formation of the Electron-Dense Core in Wild-Type and Mutant Strains of Mycoplasma pneumoniae.
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Characterization of LppS, an adhesin of Mycoplasma conjunctivae.
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Characterization of P40, a Cytadhesin of Mycoplasma agalactiae.
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Characterization of a Mycoplasma pneumoniae hmw3 Mutant: Implications for Attachment Organelle Assembly.
M. J. Willby and D. C. Krause (2002)
J. Bacteriol. 184, 3061-3068
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Force and Velocity of Mycoplasma mobile Gliding.
M. Miyata, W. S. Ryu, and H. C. Berg (2002)
J. Bacteriol. 184, 1827-1831
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Stability of Mycoplasma pneumoniae Cytadherence-Accessory Protein HMW1 Correlates with Its Association with the Triton Shell.
M. F. Balish, T.-W. Hahn, P. L. Popham, and D. C. Krause (2001)
J. Bacteriol. 183, 3680-3688
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Visualization of the Attachment Organelle and Cytadherence Proteins of Mycoplasma pneumoniae by Immunofluorescence Microscopy.
S. Seto, G. Layh-Schmitt, T. Kenri, and M. Miyata (2001)
J. Bacteriol. 183, 1621-1630
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Characterization of an Axonemal Dynein Heavy Chain Expressed Early in Airway Epithelial Ciliogenesis.
W. Reed, J. L. Carson, B. M. Moats-Staats, T. Lucier, P.-c. Hu, L. Brighton, T. M. Gambling, C.-H. Huang, M. W. Leigh, and A. M. Collier (2000)
Am. J. Respir. Cell Mol. Biol. 23, 734-741
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Identification of a New Variable Sequence in the P1 Cytadhesin Gene of Mycoplasma pneumoniae: Evidence for the Generation of Antigenic Variation by DNA Recombination between Repetitive Sequences.
T. Kenri, R. Taniguchi, Y. Sasaki, N. Okazaki, M. Narita, K. Izumikawa, M. Umetsu, and T. Sasaki (1999)
Infect. Immun. 67, 4557-4562
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