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Science 16 April 1982:
Vol. 216. no. 4543, pp. 257 - 265
DOI: 10.1126/science.7063884
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Articles

Science, Vol 216, Issue 4543, 257-265
Copyright © 1982 by American Association for the Advancement of Science

articles

Genetic mapping in mammals: chromosome map of domestic cat

SJ O'Brien and WG Nash

A genetic map of 31 biochemical loci located on 17 feline syntenic (linkage) groups has been derived by somatic cell genetic analysis of cat-rodent hybrids. Most of these syntenic groups have been assigned to one of the 19 feline chromosomes. Comparative linkage analysis of the feline biochemical loci and homologous human loci revealed considerable conservation of linkage associations between the primates and the Felidae (order Carnivora). Many of these same linkage groups have not been conserved in the murine genome. The genetic and evolutionary implications of comparative mapping analysis among mammalian species are discussed.


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