Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 2 April 1982:
Vol. 216. no. 4541, pp. 55 - 56
DOI: 10.1126/science.7063869
Prev | Table of Contents | Next

Articles

Science, Vol 216, Issue 4541, 55-56
Copyright © 1982 by American Association for the Advancement of Science

articles

Queuine, a modified base incorporated posttranscriptionally into eukaryotic transfer RNA: wide distribution in nature

Katze JR, B Basile, and JA McCloskey

Queuine, a modified base found in transfer RNA, appears to be a new dietary factor because (i) previous studies have shown that mice require it for the expression of queuine-containing transfer RNA's but apparently do not synthesize it, and (ii) significant amounts of free queuine are present in common plant and animal food products.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Queuosine Formation in Eukaryotic tRNA Occurs via a Mitochondria-localized Heteromeric Transglycosylase.
C. Boland, P. Hayes, I. Santa-Maria, S. Nishimura, and V. P. Kelly (2009)
J. Biol. Chem. 284, 18218-18227
   Abstract »    Full Text »    PDF »
Identification of Four Genes Necessary for Biosynthesis of the Modified Nucleoside Queuosine.
J. S. Reader, D. Metzgar, P. Schimmel, and V. de Crecy-Lagard (2004)
J. Biol. Chem. 279, 6280-6285
   Abstract »    Full Text »    PDF »
Biosynthesis of Archaeosine, a Novel Derivative of 7-Deazaguanosine Specific to Archaeal tRNA, Proceeds via a Pathway Involving Base Replacement on the tRNA Polynucleotide Chain.
M. Watanabe, M. Matsuo, S. Tanaka, H. Akimoto, S. Asahi, S. Nishimura, J. R. Katze, T. Hashizume, P. F. Crain, J. A. McCloskey, et al. (1997)
J. Biol. Chem. 272, 20146-20151
   Abstract »    Full Text »    PDF »
The Absence of the Diet-Derived 7-Deazapurine, Queuine in Artificial Liquid Diets.
J. P. Reyniers, J. Katze, and W.R. Farkas (1989)
JPEN J Parenter Enteral Nutr 13, 542-544
   Abstract »    PDF »
Hypermodification of tRNA in Thermophilic Archaea. CLONING, OVEREXPRESSION, AND CHARACTERIZATION OF tRNA-GUANINE TRANSGLYCOSYLASE FROM METHANOCOCCUS JANNASCHII.
Y. Bai, D. T. Fox, J. A. Lacy, S. G. Van Lanen, and D. Iwata-Reuyl (2000)
J. Biol. Chem. 275, 28731-28738
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)