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Science 12 March 1982:
Vol. 215. no. 4538, pp. 1407 - 1409
DOI: 10.1126/science.7063851
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Articles

Science, Vol 215, Issue 4538, 1407-1409
Copyright © 1982 by American Association for the Advancement of Science

articles

Suprachiasmatic stimulation phase shifts rodent circadian rhythms

B Rusak and G Groos

The integrity of the suprachiasmatic nuclei (SCN) of the hypothalamus is essential to the expression of normal circadian rhythms in rodents. Electrical stimulation of the SCN caused phase shifts and period changes in the freerunning feeding rhythms of rats and activity rhythms of hamsters. The phase response curve for SCN stimulation appears to parallel that for light pulses. These findings strengthen the hypothesis derived from lesion studies that the SCN are the dominant light-entrained oscillators in the rodent circadian system.


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Two Distinct Retinal Projections to the Hamster Suprachiasmatic Nucleus.
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Food-Anticipatory Circadian Rhythms in Rats with Paraventricular and Lateral Hypothalamic Ablations.
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