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Science 5 March 1982:
Vol. 215. no. 4537, pp. 1257 - 1260
DOI: 10.1126/science.7036347
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Articles

Science, Vol 215, Issue 4537, 1257-1260
Copyright © 1982 by American Association for the Advancement of Science

articles

Hepatic glucose production oscillates in synchrony with the islet secretory cycle in fasting rhesus monkeys

CJ Goodner, FG Hom, and DJ Koerker

Oscillations in the concentration of plasma glucose were found to reflect large fluctuations in hepatic glucose production. The fluctuations in glucose production were synchronous with fluctuations in the concentration of plasma insulin and glucagon. This synchrony suggests that hepatic pathways are entrained to the islet cycle with a minimal time delay.


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Control Mechanisms of the Oscillations of Insulin Secretion In Vitro and In Vivo.
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Growth and transparency in the lens, an epithelial tissue, stimulated by pulses of PDGF.
B Brewitt and J. Clark (1988)
Science 242, 777-779
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