Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 5 March 1982:
Vol. 215. no. 4537, pp. 1239 - 1241
DOI: 10.1126/science.7058342
Prev | Table of Contents | Next

Articles

Science, Vol 215, Issue 4537, 1239-1241
Copyright © 1982 by American Association for the Advancement of Science

articles

Heterogeneity in epidermal basal keratinocytes: morphological and functional correlations

RM Lavker and TT Sun

Two structurally distinct populations of basal keratinocytes, nonserrated and serrated, were observed in cynomolgus monkey and human palm epidermis. Anatomical location, fine structural features, and kinetic properties suggest that nonserrated cells represent a stem cell population and that serrated cells help anchor the epidermis to the dermis.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Building Epithelial Tissues from Skin Stem Cells.
E. Fuchs and J.A. Nowak (2008)
Cold Spring Harb Symp Quant Biol
   Abstract »    PDF »
Label-retaining cells of the bladder: candidate urothelial stem cells.
E. A. Kurzrock, D. K. Lieu, L. A. deGraffenried, C. W. Chan, and R. R. Isseroff (2008)
Am J Physiol Renal Physiol 294, F1415-F1421
   Abstract »    Full Text »    PDF »
Skin stem cells: rising to the surface.
E. Fuchs (2008)
J. Cell Biol. 180, 273-284
   Abstract »    Full Text »    PDF »
Epidermal stem and progenitor cells in murine epidermis accumulate UV damage despite NER proficiency.
J. G.W. Nijhof, C. van Pelt, A. A. Mulder, D. L. Mitchell, L. H.F. Mullenders, and F. R. de Gruijl (2007)
Carcinogenesis 28, 792-800
   Abstract »    Full Text »    PDF »
Side population in adult murine epidermis exhibits phenotypic and functional characteristics of keratinocyte stem cells.
R. P. Redvers, A. Li, and P. Kaur (2006)
PNAS 103, 13168-13173
   Abstract »    Full Text »    PDF »
High Expression of p63 Combined with a Large N/C Ratio Defines a Subset of Human Limbal Epithelial Cells: Implications on Epithelial Stem Cells.
P. Arpitha, N. V. Prajna, M. Srinivasan, and V. Muthukkaruppan (2005)
Invest. Ophthalmol. Vis. Sci. 46, 3631-3636
   Abstract »    Full Text »    PDF »
Epidermal Homeostasis: The Role of the Growth Hormone and Insulin-Like Growth Factor Systems.
S. R. Edmondson, S. P. Thumiger, G. A. Werther, and C. J. Wraight (2003)
Endocr. Rev. 24, 737-764
   Abstract »    Full Text »    PDF »
Propagation and Phenotypic Preservation of Rabbit Limbal Epithelial Cells on Amniotic Membrane.
D.-Y. Wang, Y.-J. Hsueh, V. C. Yang, and J.-K. Chen (2003)
Invest. Ophthalmol. Vis. Sci. 44, 4698-4704
   Abstract »    Full Text »    PDF »
Novel Expression of Vascular Cell Adhesion Molecule-1 (CD106) by Squamous Epithelium in Experimental Acute Graft-versus-Host Disease.
J. C. Kim, D. Whitaker-Menezes, M. Deguchi, B. S. Adair, R. Korngold, and G. F. Murphy (2002)
Am. J. Pathol. 161, 763-770
   Abstract »    Full Text »    PDF »
Architectural Organization of Filiform Papillae in Normal and Black Hairy Tongue Epithelium: Dissection of Differentiation Pathways in a Complex Human Epithelium According to Their Patterns of Keratin Expression.
M. Manabe, H. W. Lim, M. Winzer, and C. A. Loomis (1999)
Arch Dermatol 135, 177-181
   Abstract »    Full Text »    PDF »
The Type I Keratin 19 Possesses Distinct and Context-dependent Assembly Properties.
J. Fradette, L. Germain, P. Seshaiah, and P. A. Coulombe (1998)
J. Biol. Chem. 273, 35176-35184
   Abstract »    Full Text »    PDF »
Translocation of the Zinc Finger Protein Basonuclin from the Mouse Germ Cell Nucleus to the Midpiece of the Spermatozoon during Spermiogenesis.
M&; G. Mahoney, W. Tang, M. M. Xiang, S. B. Moss, G. L. Gerton, J. R. Stanley, and H. Tseng (1998)
Biol Reprod 59, 388-394
   Abstract »    Full Text »
The C8/144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells.
S Lyle, M Christofidou-Solomidou, Y Liu, D. Elder, S Albelda, and G Cotsarelis (1998)
J. Cell Sci. 111, 3179-3188
   Abstract »    PDF »
Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage.
M Michel, N Torok, M. Godbout, M Lussier, P Gaudreau, A Royal, and L Germain (1996)
J. Cell Sci. 109, 1017-1028
   Abstract »    PDF »
Regional variation in distribution of EGF receptor in developing and adult corneal epithelium.
J. Zieske and M Wasson (1993)
J. Cell Sci. 106, 145-152
   Abstract »    PDF »
Nuclear proteins of the bovine esophageal epithelium. I. Monoclonal antibody W2 specifically reacts with condensed nuclei of differentiated superficial cells.
T. Tang, T. Hong, C. Lin, M. Lai, C. Liu, H. Lo, M. Wang, L. Chen, W. Chen, W Ip, et al. (1993)
J. Cell Sci. 104, 237-247
   Abstract »    PDF »
Acute Follicular Graft-vs-Host Reaction: A Distinct Clinicopathologic Presentation.
K. J. Friedman, P. E. LeBoit, and E. R. Farmer (1988)
Arch Dermatol 124, 688-691
   Abstract »    PDF »
Epidermal stem cells: Properties, markers, and location.
R. M. Lavker and T.-T. Sun (2000)
PNAS 97, 13473-13475
   Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)